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Protein Overview: nhr-85

General Information:
Name(s) found: nhr-85 / CE20150 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00003675 locus:nhr-85 Nuclear hormone receptor family member nhr-85 status:Confirmed UniProt:Q9XUK7 protein_id:CAH04734.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 336 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: dauer larval development [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRDAVRFGR VPKREKARMF EEMQKTNVQS QRDQIAIQYE NLTEVMHKIN QAFGTLQATL  60
   61 EKCTGPIYTD RCPITSNFIV IPLKAAIDFA NSIPAFLSIT QTQRVHLLQN SVFDVMLLAS 120
  121 ASASTSQHFP PGGLTYDQSS ANPIIPQAIQ SISARIRQLP PQTVPILTAI AVCQADLLPE 180
  181 SQQPMLLAER LWCVLGKLGG IQSLATAPSL LADVRTLRQW HSDRLRQMSQ ISQHFSQNLL 240
  241 IAPVAAAAPV LLPPAFLSPP ASATSTSSSS VKSEFIERHP SIASLLERPR RISSSGAQEP 300
  301 LNLSLPHVRH QVKRDVDSDE QLEEMKVSPV PTTLSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..336] PSI-BLAST 47.69897 Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.15996699473685 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.46162010671465 bayes_pls_golite062009
  • protein binding
    		•  0.33427459029264 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.15459949087509 bayes_pls_golite062009
  • DNA binding
    		•  0.14395376162921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.32

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle