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Protein Overview: CE19822

General Information:
Name(s) found: CE19822 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00009246 locus:gfm-1 Elongation factor G, mitochondrial status:Confirmed UniProt:Q9XV52 protein_id:CAB04216.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 750 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: translational termination [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    translational elongation [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    translation elongation factor activity [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]
    translation release factor activity, codon specific [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPLGRFSAV AQSRRQLNNV LRRFASNEAP SSVVVPGVRP IERIRNIGIS AHIDSGKTTV  60
   61 TERILYYAGR IDSMHEVRGK DDVGATMDFM DLERQRGITI QSAATYVDWH GTNINIIDTP 120
  121 GHVDFTVEVE RALRVLDGAV LVLCGVGGVQ SQTFTVNRQL ARYNVPFICF VNKMDRNGAT 180
  181 PLKALDGLRN KLNHNAALIH LPIGKDSNFN GIVDLVEGHA LYYEGEGGLI VRKDEIPKDL 240
  241 RVEAEDRRQE LIEHIANVDE TLGEMFLNDQ TPNVQQIHEA IRRTVVKRAF VPVLSGSALK 300
  301 NKGVQTMINS VVKYLPDPSE VVNRATVKTE TTGDEKGIIL SPKRNNDKPF VGLAFKLEAG 360
  361 KYGQLTYFRV YQGQLSKGDT VYASRDGRKV RVQRLVRMHA ADMEEITTAY AGDICATFGL 420
  421 DCHSGETFST DQNLAPHCES MHIPEPVISM AIKPVNRKDA DNFIKALTRF TKEDPTFRRE 480
  481 YNQEAKETIV SGMGELHLEI YAQRMKSEYN CPVELGKPTV AYRECLGSPY KFHFRHKKQT 540
  541 GGQGQFGEIE GVIDPLPSDR NTVVEFSDET FGNNIPKNLF PALKKGLDAI VAEGPLIKSR 600
  601 IAGIHVRIQD GSTHAVDSTE IAMINTMQNM MRESFEKANW LLLEPIMKVE ATVPTEFQGN 660
  661 VVTSLTQRNA LITTTDSTEG YATVICEAPL SDMFGYTSEL RSLTEGKGEF SMEYSRYAPT 720
  721 TLEAQDRVQA EWRQLHGIAD PNEKGKKKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..750] PSI-BLAST 1000.0 Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation release factor activity
    		•  2.49148102494524 bayes_pls_golite062009
  • translation termination factor activity
    		•  2.46464632547226 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.31269308415192 bayes_pls_golite062009
  • structural molecule activity
    		•  1.96296069933386 bayes_pls_golite062009
  • translation elongation factor activity
    		•  1.78840251801545 bayes_pls_golite062009
  • motor activity
    		•  1.49368359124081 bayes_pls_golite062009
  • microtubule motor activity
    		•  1.47358567315228 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • binding
    		•  0.872512498570204 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.555181608481691 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.499351238958464 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.368412900600617 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.337324481645901 bayes_pls_golite062009
  • kinase activity
    		•  0.237670019875888 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.205488803771958 bayes_pls_golite062009
  • protein binding
    		•  0.0913090112555771 bayes_pls_golite062009
  • DNA binding
    		•  0.0880977286684361 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle