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Protein Overview: nhr-113

General Information:
Name(s) found: nhr-113 / CE19335 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00003703 locus:nhr-113 status:Confirmed UniProt:Q9XXL8 protein_id:CAA18368.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 341 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNKNDPCRI CNDSLTSGFH FGTSCCIACA AFFRRTVKNQ FTCNANNDCV ISFEKKFTCR  60
   61 ACRYNNCLKA GMRKDYIRKI NSNYVPKQKC VNVDASRSIG TSSASSSSSE SSPLVSPIIE 120
  121 KPIGKYSKIL KRYPQELLQF YVKEVEKTIA NRRKNSSKNI LHAKSMNELM VITAHQSGSA 180
  181 MEACINCPGV SKLHQKDIRV LHKYFQFLNV WLDSVREYSM SDGAHYEIGV DRKLSEFIHQ 240
  241 VRTTLGSSLA NLKLNMYEYS AFKLFCIWNL KFHKTSTALK IVAQEHYEGV CSALRNYYET 300
  301 QTKMDDFEIA IRIGDITLQI VTVSDIYHDF IKLLLNSGIS I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] PSI-BLAST 19.0 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [99..341] PSI-BLAST 30.0 Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.31508164334985 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  2.20996397516696 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.02157665604796 bayes_pls_golite062009
  • DNA binding
    		•  1.47175550190876 bayes_pls_golite062009
  • signal transducer activity
    		•  1.430912689846 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.430912689846 bayes_pls_golite062009
  • protein binding
    		•  1.34648900580465 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.29377568150934 bayes_pls_golite062009
  • receptor activity
    		•  1.17902442273252 bayes_pls_golite062009
  • transcription activator activity
    		•  0.96843436755116 bayes_pls_golite062009
  • transcription factor activity
    		•  0.92060883178562 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.67007540744134 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle