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Protein Overview: hmit-1.2

General Information:
Name(s) found: hmit-1.2 / CE19202 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00013074 locus:hmit-1.2 status:Partially_confirmed UniProt:Q9XXQ9 protein_id:CAA16405.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 613 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    drug transport [IEALink to PubMed article]
    carbohydrate transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: carbohydrate transmembrane transporter activity [IEALink to PubMed article]
    ion transmembrane transporter activity [IEALink to PubMed article]
    sugar:hydrogen symporter activity [IEALink to PubMed article]
    drug transmembrane transporter activity [IEALink to PubMed article]
    transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAVEFKVSE SGRPRPEKNP KLGFFVYLLG SAAIIGGFLF GYDTSVVSAA MLYVPEAPGL  60
   61 KPMGTVWKEV IVSITPGMAA VGAWFSGAGS DRYGRKPIII GSTLIFVCGA VICAVAWTKI 120
  121 VMLIGRIFLG VGIGFASMVV PVYLGEASPT HVRGTLVSAF AMMISFGQVV ANIMGGVFSY 180
  181 WEPYTIGWRL MFAFAGIPAL IQFVCFIFLP ETPRWLYENG HTEQAEQVLE KIYGGNTEWI 240
  241 EYELAEIKTY AEERQKQMEE EKKSGPVIWR ILKTPHVLKA CFIGSMLQAF QQLAGINTIL 300
  301 YYTADIIRSA GIENYHTIIW ISVILSICNL IGPFAPMFFI EKLGRRKLFL FSCAGVVVSL 360
  361 VLIGVSFLLV GNDSAPNFDR SAYLLAGNYQ SNGEAESCLM LSNCDSCVTS EHCGFCEDSE 420
  421 TRTGFCLPVD HNDVTLYSST GLCTNGLDKS NSSFPNATSY VWQKHHCTTS YTILPIVMMG 480
  481 VYLLTFSCGF TSLPWVLNSE FYPMWARSTC VSISTLSNWV FNLIIALTYL SLTHAITKYG 540
  541 AFWLYAIFTI IAFIFIYFLV PETTGYSIDE VEMLFMNKRQ RNIAMQARQA KLDAASDKDK 600
  601 NSSTSLSTET ITM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..467] PSI-BLAST 23.045757 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
    2 View Details [468..613] FFAS03 1.21 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.46605775041083 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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