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Protein Overview: CE18087

General Information:
Name(s) found: CE18087 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00010941 locus:gss-1 status:Confirmed UniProt:Q21549 protein_id:CAB01655.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    glutathione biosynthetic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    glutathione synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKDDRILL LNAPRLPLED DKLNELTADL HDWAHANGLV MRLSTDKLSS EVCQTTPLTL  60
   61 LPSPFPKNVF EEAVHIQNLF ASLYHFIAYE FDFLIDIHKN VVKTDDFTRN MVEILKKVKA 120
  121 QGLKQPVTLA IQRSDYMCHK DQYSAEYGLK QIEINNIASS MGAHALRLTE WHIRVLKALN 180
  181 ISDDVIQRAI PENKPIPMIA EALFKAWSHF SNPAAVVLVV VENVNQNQID QRHVEYELEK 240
  241 LGVPMTCIIR RNLTQCYEQL SLNDRSDLMI DGRQVAIVYF RAGYSPDHYP STKEWEARER 300
  301 MELSTAIKTP WIGLQVANTK KTQQVLSEDG VLERFIGKPR EARDIRASFA GMWALENTDE 360
  361 VTMKVVAGAQ KHPEAFVLKP QTEGGAALHT GDEMVQMLRE LPEEERGAFI LMEKLKPMII 420
  421 ENYLVLAKKP ITFAKAVSEL GVYGYAFGRK DAPELKTAGH LLRTKPESTA MGGVAAGHAV 480
  481 VDTPFLYEFI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..490] PSI-BLAST 1000.0 Eukaryotic glutathione synthetase, substrate-binding domain; Eukaryotic glutathione synthetase ATP-binding domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutathione binding
    		•  3.43434843798286 bayes_pls_golite062009
  • ligase activity
    		•  3.25077459445999 bayes_pls_golite062009
  • glutathione synthase activity
    		•  3.18460876432532 bayes_pls_golite062009
  • catalytic activity
    		•  2.5009559386228 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  1.59015373957506 bayes_pls_golite062009
  • succinate-CoA ligase activity
    		•  1.52785506428706 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  1.44257510787161 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  0.935432886482705 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  0.78189952793438 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.599203164789408 bayes_pls_golite062009
  • CoA-ligase activity
    		•  0.51228075142462 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  0.448084116680826 bayes_pls_golite062009
  • binding
    		•  0.374385700553659 bayes_pls_golite062009
  • succinate-CoA ligase (ADP-forming) activity
    		•  0.324506681366243 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.239594107637156 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle