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Protein Overview: exo-3

General Information:
Name(s) found: exo-3 / CE16306 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00001372 locus:exo-3 status:Confirmed UniProt:G5EBR7 protein_id:CAB03235.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 288 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: embryonic development [IMPLink to PubMed article]
    DNA repair [IEALink to PubMed article][IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    endonuclease activity [IEALink to PubMed article]
    nuclease activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRKAEEAP APKLASIFTK KVKPAEEDNN QKSWKFVCWN VAGLRACVKK SDFKEVLAEE  60
   61 PDLVFLGETK CKEWPPEMEE TFKNYTKTLV VSTEKNGGYA GVGLLSKCAP MKVHKGIGDP 120
  121 EFDTAGRLII AEFSKFYFIG AYVPNSGAKL VNLEKRGRWE KLLTEKMKEM DEKKPVIYGG 180
  181 DLNVAHNEID LKNPESNRNK TAGFTDQERG WFSEMLELGF TDTFRAMHPD EKKYSFWSYL 240
  241 ANSRQKDVGW RLDYYVVSNR IMNKVKRSDI MSSVMGSDHA PVVMQIDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] PSI-BLAST 65.0 THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • exonuclease activity
    		•  2.70644978530491 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  2.57658637220545 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  2.54419310609558 bayes_pls_golite062009
  • hydrolase activity
    		•  2.50832753420463 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.36841783202726 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  1.8139951607534 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  1.7967853371745 bayes_pls_golite062009
  • nuclease activity
    		•  1.78432551160775 bayes_pls_golite062009
  • catalytic activity
    		•  1.76511376991978 bayes_pls_golite062009
  • binding
    		•  1.74593496417303 bayes_pls_golite062009
  • DNA binding
    		•  0.961734136090079 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.947430734766989 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.597390739522692 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.58571720340663 bayes_pls_golite062009
  • transcription factor binding
    		•  0.55477888309075 bayes_pls_golite062009
  • protein binding
    		•  0.476649214025345 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  0.228910502815798 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.100365481550461 bayes_pls_golite062009
  • phosphatase activity
    		•  0.00559251346312178 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle