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Protein Overview: CE15651

General Information:
Name(s) found: CE15651 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00007824 status:Confirmed UniProt:O45279 protein_id:CAB02813.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 337 amino acids

    Gene Ontology:
    Cellular Component: pyruvate dehydrogenase complex [IEALink to PubMed article]
    oxoglutarate dehydrogenase complex [IEALink to PubMed article]
    Biological Process: metabolic process [IEALink to PubMed article]
    glycolysis [IEALink to PubMed article]
    tricarboxylic acid cycle [IEALink to PubMed article]
    pyruvate metabolic process [IEALink to PubMed article]
    Molecular Function: dihydrolipoyllysine-residue succinyltransferase activity [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]
    acyltransferase activity [IEALink to PubMed article]
    dihydrolipoyllysine-residue acetyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAGSQALRH LSTAAQNQGA CGPAVKLLLI QYGLENRKID GTGPKNKNIL KGDVMKIVEA  60
   61 EKLKPVAHHA HAPKETHIEN KSIEKKSDIF GANNRSLRHH QDIPLSNIRA TIAKRLTASK 120
  121 QQIPHEYQGV DVRIDDILAL RQKLKKSGTA VSLNDFIIKA AALALRSVPT VNVRWTPEGI 180
  181 GLGSVDISVA VATPTGLITP IVENSDILGV LAISSKVKEL SGLARESKLK PQQFQGGSFT 240
  241 ISNLGMFGSV TNFTAIINPP QCAILTIGGT RSEVVSVDGQ LETQKLMGVN LCFDGRAISE 300
  301 ECAKRFLLHF SESLSDPELL IAEPLSPELD FDFSRLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] PSI-BLAST 9.522879 Solution structure of the e3_binding domain of dihydrolipoamide branched chaintransacylase
    2 View Details [90..337] PSI-BLAST 84.522879 Dihydrolipoamide succinyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  9.65061123545754 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  9.64995677986911 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  9.49696044977584 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  8.45313874919036 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  8.17557182322815 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  6.40483178382327 bayes_pls_golite062009
  • acetyltransferase activity
    		•  6.08159176722072 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  5.93985773477717 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  5.74314131636952 bayes_pls_golite062009
  • acyltransferase activity
    		•  5.72047003788767 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  5.47973101916847 bayes_pls_golite062009
  • S-succinyltransferase activity
    		•  4.10308166636667 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  4.10308166636667 bayes_pls_golite062009
  • carnitine O-acyltransferase activity
    		•  2.07401053954424 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.78431187655869 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • succinyltransferase activity
    		•  1.14502959978145 bayes_pls_golite062009
  • transferase activity
    		•  1.08341671157927 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  0.731328511162172 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  0.203430690130141 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  0.0797707245124104 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  0.0797707245124104 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle