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Protein Overview: CE13279

General Information:
Name(s) found: CE13279 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00020269 locus:erfa-1 status:Confirmed UniProt:S6EZT6 protein_id:CDG24149.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 443 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: translational termination [IEALink to PubMed article]
    nematode larval development [IMP]
    locomotion [IMP]
    embryonic development ending in birth or egg hatching [IMP]
    receptor-mediated endocytosis [IMP]
    reproduction [IMP]
    growth [IMP]
    Molecular Function: serine-type peptidase activity [IEALink to PubMed article]
    translation release factor activity, codon specific [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAPAAGATA GGDDAADRNV EMWKIKRLIK SLELARGNGT SMISLIIPPK DQVARIQRML  60
   61 AEEYGTASNI KSRVNRLSVL GAITSVQGRL KLYNKVPPNG LVVYCGTIMT DEGKEKKVNI 120
  121 DFEPFKAINT SLYLCDNKFH TEALQGLLAD DNKFGFIIMD GNGCLFGTLQ GNTREVLHKF 180
  181 TVDLPKKHGR GGQSAVRFAR LRNEKRHNYV RKVAENSVEQ FIKNDKVTVA GLILAGSADF 240
  241 KTELGQSDMF DQRLQAKMIK TVDIAYGGEN GFNQAIELAA DTLASVKFIQ EKKLIGGYFD 300
  301 EISQDTGKYV FGVKDTLAAL EMGAIETLIC WENLDIVRYK MKNSLGEDIL LNLRPDEEKD 360
  361 KSHFTDSETG QDMEIIETMP LLEWFANNYK NFGAALEIVT DKSQEGAQFV RGFGGIGGLL 420
  421 RYRVDLAHVD LEDELDNIDL DDY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..443] PSI-BLAST 169.0 Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation release factor activity
    		•  11.5102558694213 bayes_pls_golite062009
  • translation termination factor activity
    		•  11.4768548464911 bayes_pls_golite062009
  • translation release factor activity, codon specific
    		•  7.66455753522311 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.97154934968642 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.70960972397471 bayes_pls_golite062009
  • structural molecule activity
    		•  2.64319832043379 bayes_pls_golite062009
  • binding
    		•  2.24516466558786 bayes_pls_golite062009
  • translation regulator activity
    		•  1.83257472130927 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.81472167858216 bayes_pls_golite062009
  • RNA binding
    		•  1.59103459949328 bayes_pls_golite062009
  • mRNA binding
    		•  0.607146672130391 bayes_pls_golite062009
  • protein binding
    		•  0.381324299701367 bayes_pls_golite062009
  • catalytic activity
    		•  0.264002643439785 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle