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View Structure Prediction Details

Protein: CE13279
Organism: Caenorhabditis elegans
Length: 443 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE13279.

Description E-value Query
Range
Subject
Range
gi|220944832, gi... - gi|220954670|gb|ACL89878.1| eRF1-PA [synthetic construct], gi|220944832|gb|ACL84959.1| eRF1-PA [synt...
gi|194118161, gi... - gi|195160369|ref|XP_002021048.1| GL25132 [Drosophila persimilis], gi|194118161|gb|EDW40204.1| GL2513...
eRF1-PC, eRF1-PB... - The gene eukaryotic release factor 1 is referred to in FlyBase by the symbol Dmel\eRF1 (CG5605, FBgn...
590.0 [0..9] [443..1]

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Predicted Domain #1
Region A:
Residues: [1-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAPAAGATA GGDDAADRNV EMWKIKRLIK SLELARGNGT SMISLIIPPK DQVARIQRML  60
   61 AEEYGTASNI KSRVNRLSVL GAITSVQGRL KLYNKVPPNG LVVYCGTIMT DEGKEKKVNI 120
  121 DFEPFKAINT SLYLCDNKFH TEALQGLLAD DNKFGFIIMD GNGCLFGTLQ GNTREVLHKF 180
  181 TVDLPKKHGR GGQSAVRFAR LRNEKRHNYV RKVAENSVEQ FIKNDKVTVA GLILAGSADF 240
  241 KTELGQSDMF DQRLQAKMIK TVDIAYGGEN GFNQAIELAA DTLASVKFIQ EKKLIGGYFD 300
  301 EISQDTGKYV FGVKDTLAAL EMGAIETLIC WENLDIVRYK MKNSLGEDIL LNLRPDEEKD 360
  361 KSHFTDSETG QDMEIIETMP LLEWFANNYK NFGAALEIVT DKSQEGAQFV RGFGGIGGLL 420
  421 RYRVDLAHVD LEDELDNIDL DDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 169.0
Match: 1dt9A
Description: Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation release factor activity 11.5102558694213 bayes_pls_golite062009
translation termination factor activity 11.4768548464911 bayes_pls_golite062009
translation release factor activity, codon specific 7.66455753522311 bayes_pls_golite062009
structural constituent of ribosome 2.97154934968642 bayes_pls_golite062009
nucleic acid binding 2.70960972397471 bayes_pls_golite062009
structural molecule activity 2.64319832043379 bayes_pls_golite062009
binding 2.24516466558786 bayes_pls_golite062009
translation regulator activity 1.83257472130927 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.81472167858216 bayes_pls_golite062009
RNA binding 1.59103459949328 bayes_pls_golite062009
mRNA binding 0.607146672130391 bayes_pls_golite062009
protein binding 0.381324299701367 bayes_pls_golite062009
catalytic activity 0.264002643439785 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle