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Protein Overview: cif-1

General Information:
Name(s) found: cif-1 / CE11954 [WormBase]
Description(s) found:
Found 24 descriptions.
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  • WBGene00019543 locus:cif-1 COP9\/Signalosome and eIF3 complex-shared subunit 1 status:Confirmed UniProt:Q94261 protein_id:CCD68723.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 390 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTRELPVF AYIDDVKQLQ ELRQYLNKHD SVKLDPNGPS ETAQNMIEIC STLNVLPSWS  60
   61 QDVDLVLNSI SSLIVVVPGE KCEPVVDSFI KNVAPQFYKG TGWASHAGIA VRVLSNLYKG 120
  121 YSNFHTVQEK IFKALVDMCA EARLIGELEC NLETLQDRFN TWKTPVEGQR EILRAVHRAL 180
  181 LVDQRVDQAA KVMTALLGTY TEKDAAAARD DAMECVRTAV VDPKSFSFDH LERLSAVKAL 240
  241 KTSDPLMFTA LELFISGTLK DYKEFVAKNP KFVTEHLKVD ETILLKKIRL LTLMSLAEEK 300
  301 NEISLDELAK QLDILADETL EEFVIDAIQV NAISGKINEM ARTLIVSSYQ HRRFGTEQWV 360
  361 LLEKRLKVLI ANLKQTHNNV HEVNQRIEAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..76] deduced N/A No confident structure predictions are available.
    2 View Details [77..287] MSA 6.422997 View MSA. No confident structure predictions are available.
    3 View Details [288..390] PSI-BLAST 9.0 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.95153041057228 bayes_pls_golite062009
  • DNA binding
    		•  2.31496579551752 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.93897246216986 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.83610835165707 bayes_pls_golite062009
  • transcription factor activity
    		•  1.75197559197272 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.04956049764478 bayes_pls_golite062009
  • protein binding
    		•  0.776629952382685 bayes_pls_golite062009
  • transcription activator activity
    		•  0.57320482892428 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.363241395353229 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.12259689863474 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle