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View Structure Prediction Details

Protein: cif-1
Organism: Caenorhabditis elegans
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cif-1.

Description E-value Query
Range
Subject
Range
gi|109470435, gi... - gi|109470435|ref|XP_001079651.1| PREDICTED: similar to dendritic cell protein GA17 [Rattus norvegicu...
241.0 [0..2] [380..75]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTRELPVF AYIDDVKQLQ ELRQYLNKHD SVKLDPNGPS ETAQNMIEIC STLNVLPSWS  60
   61 QDVDLVLNSI SSLIVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [77-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPGEKCEPVV DSFIKNVAPQ FYKGTGWASH AGIAVRVLSN LYKGYSNFHT VQEKIFKALV  60
   61 DMCAEARLIG ELECNLETLQ DRFNTWKTPV EGQREILRAV HRALLVDQRV DQAAKVMTAL 120
  121 LGTYTEKDAA AARDDAMECV RTAVVDPKSF SFDHLERLSA VKALKTSDPL MFTALELFIS 180
  181 GTLKDYKEFV AKNPKFVTEH LKVDETILLK K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [288-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRLLTLMSLA EEKNEISLDE LAKQLDILAD ETLEEFVIDA IQVNAISGKI NEMARTLIVS  60
   61 SYQHRRFGTE QWVLLEKRLK VLIANLKQTH NNVHEVNQRI EAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.95153041057228 bayes_pls_golite062009
DNA binding 2.31496579551752 bayes_pls_golite062009
transcription regulator activity 1.93897246216986 bayes_pls_golite062009
nucleic acid binding 1.83610835165707 bayes_pls_golite062009
transcription factor activity 1.75197559197272 bayes_pls_golite062009
sequence-specific DNA binding 1.04956049764478 bayes_pls_golite062009
protein binding 0.776629952382685 bayes_pls_golite062009
transcription activator activity 0.57320482892428 bayes_pls_golite062009
transcription repressor activity 0.363241395353229 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.12259689863474 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle