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Protein Overview: mkk-4

General Information:
Name(s) found: mkk-4 / CE10328 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00003368 locus:mkk-4 MAP kinase kinase mkk-4 status:Confirmed UniProt:Q20347 protein_id:CAA88264.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: activation of MAPK activity [IGILink to PubMed article]
    regulation of synapse organization [IGILink to PubMed article][IMPLink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    mitogen-activated protein kinase kinase kinase binding [IPILink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQEDDENLR NSMSLRPTSL STRPTSLSVN GNEKTLPEES VLRSLSTGTL KYPDDEHLYT  60
   61 FSSANLQDLG AIGNGNFGTV YKMRHKETGK LIAVKRIRCN NIGHREQIRL LREHDTIVKS 120
  121 EKGPNIVKFY GAIFSEGDCW ICMELMDISM DLLYKRVYMV KNSRLNENVV GHITVCTVDA 180
  181 LDYLKKELKI IHRDVKPSNI LVDGTGAVKL CDFGICGQLE ESFAKTHDAG CQPYLAPERI 240
  241 TSSDKYDVRS DVWSLGITLY EIATGKFPYQ EWNSLFDQIA TVVSGDPPIL HPDSDDFHYS 300
  301 LPLVKFINTC LTKDRRHRPK YDTLKSFDFY RIYAVAGPEI EEAKRILGVE AIDTRNHPVD 360
  361 HRG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..363] PSI-BLAST 47.39794 No description for 2dylA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle