Protein Overview: CE08817

General Information:
Name(s) found:	CE08817 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00016750 status:Confirmed UniProt:Q8IG67 protein_id:CCD64205.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	544 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	transcription [IEA] nematode larval development [IMP ] positive regulation of growth rate [IMP] gamete generation [IMP] growth [IMP ] positive regulation of multicellular organism growth [IMP]
Molecular Function:	DNA binding [IEA] DNA-directed RNA polymerase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGGKYETQM CVIIIEDIFG KIVAKVMETI LKESCQLSTL FYKLKGQISN TLIRKSVSTL  60
   61 INFGFVTFHL DTNNRTTYVA DSDQIQHVIS SPRACLIAKT LYGPAAESIC VELISQGRLT 120
  121 VSETIRRIQA TDETAVFSDI KKSFEELAAA HFLIRVPSVE SEIHGCPQFV TNFDPFAIST 180
  181 NIMEKKEGTS TSDSTSNNRK RKADSTPEDG DAGQYWRINW IRFNGYLRDE LIIDYLIGGG 240
  241 SKGTMTNLNV KKEETIEDPQ GDRTQYITQN VAHLMFKINE TRAKPMSMES ITASLTDLQR 300
  301 LVKENGLNLA KPDIELACQI LVDESDGIIR KLGESNGGIF IVDIRRAIRQ ICRHHCESLI 360
  361 REQFEGRAIR VMRLLENRHY LDEEQVEKLS MMSGKEAREM LYALVEEGYV FNKPVGRSND 420
  421 FQPARTFYLY YVDLPRTIRG LVEYTCKLVR NLIVRQRHER TENKSVLDKD ANVQPIIENI 480
  481 RSSEQLDEAS KLAQIAEVEE MYLPGPDRAQ LNRFRKAQAT LLAAQDQSIR VLLSFKLFLA 540
  541 SGEN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..129]	Pfam	21.522879	No description for PF08221.2 was found. No confident structure predictions are available.
2	View Details	[130..291]	deduced	N/A	No confident structure predictions are available.
3	View Details	[292..471]	PSI-BLAST	4.0	An extended winged helix domain in general transcription factor E/IIE alpha
4	View Details	[472..544]	MSA	1.043984	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

No functions predicted.

3

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
DNA-directed RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
nucleotidyltransferase activity	2.80876790343695	bayes_pls_golite062009
sequence-specific DNA binding	2.48053910222825	bayes_pls_golite062009
transcription activator activity	2.37668609508629	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
transferase activity	2.17455387041569	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.13327310661537	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.70025468248325	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.461477365615935	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.0856082199488197	bayes_pls_golite062009

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle