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Protein Overview: CE08718

General Information:
Name(s) found: CE08718 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00016653 status:Confirmed UniProt:O01806 protein_id:CCD67305.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 396 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    ribonucleoprotein complex [IEALink to PubMed article]
    Biological Process: negative regulation of vulval development [IMPLink to PubMed article]
    gonad development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGETAAAVHD DADQKIIKQL EYYFGNINLP RDKFLQEKLK EDDGWVPITT MLNFNRLASI  60
   61 SKDTEKIANA VKNSGSGIIS VSEDNQKIRR NEENPVPENS LEYWQKIKHR TVYMKGFSTD 120
  121 TQLDDIIQWA NQFGETENVL MRRLKPGDRT FKGSVFITYK TREEAEAAQK AEVKFGETEL 180
  181 TKMMQDEYWT LKNKETKEAR AANKAAKSAK NTSEAIESEK AQHAVRYEKG LILAVDGLGP 240
  241 DSTIDSIKTF FKLHGSVGYV AHENGGKTAE IRFNNDSEGA QKAWDNAVAA GTDGKVILQE 300
  301 AELSARVLDG EEEEKYWTEF NARKNQRQGG GRGGRGGRGG RGGRGGRGGR GGRGGRGDRR 360
  361 GDKRSANDEG ADGSDEPKAK RTVFAEDGAP AAAAAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] PSI-BLAST 23.0 Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen
    2 View Details [91..172] PSI-BLAST 14.154902 No description for 2dh7A was found.
    3 View Details [173..396] PSI-BLAST 12.221849 CG8781 protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.04426015975991 bayes_pls_golite062009
  • binding
    		•  1.99063774159045 bayes_pls_golite062009
  • DNA binding
    		•  1.63968725174405 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.51035375793093 bayes_pls_golite062009
  • transcription factor activity
    		•  1.16072080355661 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.55739080981393 bayes_pls_golite062009
  • transcription activator activity
    		•  0.14130464856269 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.13573040816325 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.10590295737522 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43479844212501 bayes_pls_golite062009
  • RNA binding
    		•  0.863532182990129 bayes_pls_golite062009
  • protein binding
    		•  0.303849616374798 bayes_pls_golite062009
  • mRNA binding
    		•  0.0677652340577004 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle