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Protein Overview: CE08620

General Information:
Name(s) found: CE08620 [WormBase]
Description(s) found:
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  • WBGene00007993 locus:idhb-1 Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial status:Confirmed UniProt:Q93353 protein_id:CAB02822.1 [WormBase]
  • pir||T19810 hypothetical protein C37E2.1 - Caenorhabditis elegans [NCBI NR]
  • gi|3874853|emb|CAB02822.1| C. elegans protein C37E2.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|3024009|sp|Q93353.1|IDH3B_CAEEL RecName: Full=Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; AltName: Full=Isocitric dehydrogenase; AltName: Full=NAD(+)-specific ICDH; Flags: Precursor [NCBI NR]
  • gi|17550882|ref|NP_510362.1| hypothetical protein C37E2.1 [Caenorhabditis elegans] [NCBI NR]
  • (Q93353) Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD+-specific ICDH) [Swiss-Prot]
  • Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Caenorhabditis elegans GN=idhb-1 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE08620 WBGene00007993 isocitrate dehydrogenase status:Confirmed SW:Q93353 protein_id:CAB02822.1 [wormpep150.fasta]
  • 08620 WBGene00007993 isocitrate dehydrogenase status:Confirmed TR:Q93353 protein_id:CAB02822.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • isocitrate dehydrogenase (41.6 kD) (XO790) [Caenorhabditis elegans]gi|3874853|emb|CAB02822.1| Hypothetical protein C37E2.1 [Caenorhabditis elegans]gi|7497159|pir||T19810 hypothetical protein C37E2.1 - Caenorhabditis elegansgi|3024009|sp|Q93353|IDHB_CAE [nrdb_11152004_Chlamydomonas]
  • CE08620 WBGene00007993 isocitrate dehydrogenase status:Confirmed TR:Q93353 protein_id:CAB02822.1 [wormpep132.fasta]
  • 08620 WBGene00007993 isocitrate dehydrogenase status:Confirmed SW:Q93353 protein_id:CAB02822.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • isocitrate dehydrogenase status:Confirmed SW:Q93353 protein_id:CAB02822.1 [wormpep115.fasta.reversed]
  • CE08620 isocitrate dehydrogenase status:Partially_confirmed SW:Q93353 protein_id:CAB02822.1 [wormpep80.hongbin]
  • CE08620 WBGene00007993 isocitrate dehydrogenase status:Confirmed UniProt:Q93353 protein_id:CAB02822.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE08620 WBGene00007993 isocitrate dehydrogenase status:Confirmed UniProt:Q93353 protein_id:CAB02822.1| [wormORF-contam.fasta]
  • Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor (Isocitric dehydrogenase) (NAD(+)-specific ICDH) [nr-271106-contam.fasta]
  • C37E2.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C37E2.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE08620 WBGene00007993 locus:idhb-1 isocitrate dehydrogenase status:Confirmed UniProt:Q93353 protein_id:CAB02822.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE08620 WBGene00007993 locus:idhb-1 status:Confirmed UniProt:Q93353 protein_id:CAB02822.1 Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    mitochondrion [IEALink to PubMed article]
    Biological Process: metabolic process [IEALink to PubMed article]
    leucine biosynthetic process [IEALink to PubMed article]
    tricarboxylic acid cycle [IEALink to PubMed article]
    Molecular Function: isocitrate dehydrogenase (NAD+) activity [IEALink to PubMed article]
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    isocitrate dehydrogenase (NADP+) activity [IEALink to PubMed article]
    tartrate dehydrogenase activity [IEALink to PubMed article]
    3-isopropylmalate dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRTVSSLS RVAPQTLGAV NAASSRQYSI TAPRPPTELN QKLKVTIIPG DGVGPELIYT  60
   61 VQDIVKQTGI PIEFEEIFLS EVHYTRSSSI ENAVESIGRN NNVALKGAIE ESAVLHTEGE 120
  121 LQGLNMRLRR SLDLFANVVH IKTLDGIKTR HGKQLDFVIV REQTEGEYSS LEHELVPGVI 180
  181 ECLKISTRTK AERIAKFAFD YATKTGRKKV TAVHKANIMK LGDGLFLRTC EGVAKQYPKI 240
  241 QFESMIIDNT CMQLVSKPEQ FDVMVMPNLY GNIIDNLAAG LVGGAGVVPG QSVGRDFVIF 300
  301 EPGSRHSFQE AMGRSIANPT AMILCAANML NHLHLDAWGN SLRQAVADVV KEGKVRTRDL 360
  361 GGYATTVDFA DAVIDKFRI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..379] PSI-BLAST 100.0 No description for 2d1cA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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