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Protein Overview: sptl-1

General Information:
Name(s) found: sptl-1 / CE08323 [WormBase]
Description(s) found:
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  • WBGene00016020 locus:sptl-1 Serine palmitoyltransferase 1 status:Confirmed UniProt:P91079 protein_id:CCD65323.1 [WormBase]
  • pir||T25557 hypothetical protein C23H3.4 - Caenorhabditis elegans [NCBI NR]
  • gi|71982617|ref|NP_001021978.1| Serine Palmitoyl Transferase famiLy family member (sptl-1) [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_493648.1| serine palmitoyltransferase 1 (52.1 kD) (2A347) [Caenorhabditis elegans] [NCBI NR]
  • gi|13592347|gb|AAK31446.1| Serine palmitoyl transferase family protein 1, isoform a [Caenorhabditis elegans] [NCBI NR]
  • Serine palmitoyltransferase 1 OS=Caenorhabditis elegans GN=sptl-1 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE08323 WBGene00016020 locus:sptl-1 aminotransferase status:Partially_confirmed TR:P91079 protein_id:AAK31446.1 [wormpep150.fasta]
  • 08323 WBGene00016020 aminotransferase status:Partially_confirmed TR:P91079 protein_id:AAK31446.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • serine palmitoyltransferase 1 (52.1 kD) (2A347) [Caenorhabditis elegans]gi|13592347|gb|AAK31446.1| Hypothetical protein C23H3.4 [Caenorhabditis elegans]gi|7496349|pir||T25557 hypothetical protein C23H3.4 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • CE08323 WBGene00016020 aminotransferase status:Partially_confirmed TR:P91079 protein_id:AAK31446.1 [wormpep132.fasta]
  • 08323 WBGene00016020 locus:sptl-1 aminotransferase status:Partially_confirmed TR:P91079 protein_id:AAK31446.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • aminotransferase status:Partially_confirmed TR:P91079 protein_id:AAK31446.1 [wormpep115.fasta.reversed]
  • CE08323 aminotransferase status:Partially_confirmed TR:P91079 protein_id:AAK31446.1 [wormpep80.hongbin]
  • CE08323 WBGene00016020 locus:sptl-1 aminotransferase status:Confirmed UniProt:P91079_CAEEL protein_id:AAK31446.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE08323 WBGene00016020 locus:sptl-1 aminotransferase status:Confirmed UniProt:P91079_CAEEL protein_id:AAK31446.1| [wormORF-contam.fasta]
  • Serine palmitoyl transferase family protein 1, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Serine Palmitoyl Transferase famiLy family member (sptl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE08323 WBGene00016020 locus:sptl-1 aminotransferase status:Confirmed TR:P91079 protein_id:AAK31446.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE08323 WBGene00016020 locus:sptl-1 aminotransferase status:Confirmed UniProt:P91079 protein_id:AAK31446.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE08323 WBGene00016020 locus:sptl-1 aminotransferase status:Confirmed UniProt:P91079 protein_id:CCD65323.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE08323 WBGene00016020 locus:sptl-1 status:Confirmed UniProt:P91079 protein_id:CCD65323.1 Serine palmitoyltransferase 1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    tetrapyrrole biosynthetic process [IEALink to PubMed article]
    biotin biosynthetic process [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    transferase activity, transferring nitrogenous groups [IEALink to PubMed article]
    glycine C-acetyltransferase activity [IEALink to PubMed article]
    5-aminolevulinate synthase activity [IEALink to PubMed article]
    transferase activity [IEALink to PubMed article]
    8-amino-7-oxononanoate synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFLPDSWHF YIETLLVALL AYVVMRNRSK RQQEKLSKKL TERQKDELIA DWTPEPLVPE  60
   61 TPQDHPVLNP KYADGKMTKD VSIDGEKYLN MASTNFLSFI GVKRIEDRAK QTIFKYGVGS 120
  121 CGPRGFYGTV DVHLDLEKEL AKFMGCEEAV LYSYGFATVS SAIPAYAKKG DVIFVDEGVN 180
  181 FAIQKGLQAS RSRVEYFKHN DMEHLERLLL EQEQRDKKDP KKAKSVRRFI VVEGLYVNYA 240
  241 DLCPLPKIIE FKWRFKVRVF IDESWSFGVI GKTGRGVTEH FNVPMEDVDM VMASLENALA 300
  301 STGGFCVGRS YVVGHQRLSG LGYCFSASLP PLLATAASEA ISIIDEEPSR VQKVTEMAIN 360
  361 GQKKLQDALS GSKFSLQGCP ESPMKHIYYN GEDEEKQLDT FVETVFTKNH LLLTRARYLD 420
  421 KDELFKIRPS IRVMFQHDLT EEEIQRAVDA IRVVAHKF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..458] PSI-BLAST 78.69897 2-amino-3-ketobutyrate CoA ligase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • serine C-palmitoyltransferase activity
    		•  9.1839236553858 bayes_pls_golite062009
  • C-palmitoyltransferase activity
    		•  9.1839236553858 bayes_pls_golite062009
  • C-acyltransferase activity
    		•  4.29379571948906 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  1.08684392183114 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07873942461292 bayes_pls_golite062009
  • DNA binding
    		•  0.886628214497634 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.814403324199462 bayes_pls_golite062009
  • structural molecule activity
    		•  0.811208803619077 bayes_pls_golite062009
  • transferase activity
    		•  0.737426388870721 bayes_pls_golite062009
  • binding
    		•  0.661198018681765 bayes_pls_golite062009
  • transcription factor activity
    		•  0.615294010373048 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle