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Protein Overview: pas-1

General Information:
Name(s) found: pas-1 / CE08184 [WormBase]
Description(s) found:
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  • WBGene00003922 locus:pas-1 Proteasome subunit alpha type-6 status:Confirmed UniProt:O17586 protein_id:CAB02738.1 [WormBase]
  • pir||T19320 hypothetical protein C15H11.7 - Caenorhabditis elegans [NCBI NR]
  • gi|3874351|emb|CAB02738.1| C. elegans protein C15H11.7, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17562788|ref|NP_506571.1| Proteasome Alpha Subunit family member (pas-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|12229891|sp|O17586.1|PSA6_CAEEL RecName: Full=Proteasome subunit alpha type-6; AltName: Full=Proteasome subunit alpha 1 [NCBI NR]
  • Proteasome subunit alpha type-6 OS=Caenorhabditis elegans GN=pas-1 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE08184 WBGene00003922 locus:pas-1 proteasome component (A-type) status:Confirmed SW:O17586 protein_id:CAB02738.1 [wormpep150.fasta]
  • 08184 WBGene00003922 locus:pas-1 proteasome component (A-type) status:Confirmed SW:O17586 protein_id:CAB02738.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • proteasome Alpha Subunit (27.0 kD) (pas-1) [Caenorhabditis elegans]gi|3874351|emb|CAB02738.1| Hypothetical protein C15H11.7 [Caenorhabditis elegans]gi|7496067|pir||T19320 hypothetical protein C15H11.7 - Caenorhabditis elegansgi|12229891|sp|O17586|PSA6_ [nrdb_11152004_Chlamydomonas]
  • locus:pas-1 proteasome component (A-type) status:Confirmed SW:O17586 protein_id:CAB02738.1 [wormpep115.fasta.reversed]
  • CE08184 locus:pas-1 proteasome component (A-type) status:Partially_confirmed SW:O17586 protein_id:CAB02738.1 [wormpep80.hongbin]
  • CE08184 WBGene00003922 locus:pas-1 proteasome component (A-type) status:Confirmed UniProt:PSA6_CAEEL protein_id:CAB02738.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE08184 WBGene00003922 locus:pas-1 proteasome component (A-type) status:Confirmed UniProt:PSA6_CAEEL protein_id:CAB02738.1| [wormORF-contam.fasta]
  • Hypothetical protein C15H11.7 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Proteasome subunit alpha type 6 (Proteasome subunit alpha 1) [nr-271106-contam.fasta]
  • Proteasome Alpha Subunit family member (pas-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE08184 WBGene00003922 locus:pas-1 proteasome component (A-type) status:Confirmed UniProt:O17586 protein_id:CAB02738.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE08184 WBGene00003922 locus:pas-1 status:Confirmed UniProt:O17586 protein_id:CAB02738.1 Proteasome subunit alpha type-6 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 246 amino acids

    Gene Ontology:
    Cellular Component: proteasome core complex [IEALink to PubMed article]
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    ubiquitin-dependent protein catabolic process [IEALink to PubMed article]
    Molecular Function: endopeptidase activity [IEALink to PubMed article]
    threonine-type endopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRGSSAGFD RHITIFSPEG RVYQVEYAFK AINSTNLTAV AVKGADAAVI AVQKRVPDSL  60
   61 IVADTVTSVY QISQSVGCCA IGMIPDAKFQ IKRAQGEAAS WKYKNGYDMP CELLAKKMAD 120
  121 LNQYYTQNAE MRSLGCALLF ISYDDEKGPE VYRVDPAGYY RGMKGVSVGV KQLPATSFLE 180
  181 KKIKKKSELT STEAIELAIE ALQTSLGIDV RSKDLEVVVV TKDNSKFTKL TSDQVEHHLN 240
  241 QIANRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..246] PSI-BLAST 75.0 Proteasome alpha subunit (non-catalytic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • endopeptidase activity
    		•  6.91642761177919 bayes_pls_golite062009
  • peptidase activity
    		•  6.84511694091156 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  6.5973571808298 bayes_pls_golite062009
  • hydrolase activity
    		•  4.47652590304822 bayes_pls_golite062009
  • threonine-type endopeptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • threonine-type peptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • binding
    		•  1.75265921676176 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.39216781236247 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle