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Protein Overview: CE05467

General Information:
Name(s) found: CE05467 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00008230 locus:pfk-2 Probable 6-phosphofructokinase status:Partially_confirmed UniProt:Q27483 protein_id:CAA94737.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 756 amino acids

    Gene Ontology:
    Cellular Component: 6-phosphofructokinase complex [IEALink to PubMed article]
    cytoplasm [IEALink to PubMed article]
    Biological Process: glycolysis [IEALink to PubMed article]
    fructose 6-phosphate metabolic process [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    phosphofructokinase activity [IEALink to PubMed article]
    6-phosphofructokinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQKFKKGKD HGVGVLTSGG DSQGMNAAVR SVVRETIRQG HRCYLIREGY NGLINGNIEL  60
   61 AKWAHVANVT HLGGSMIGTS RCDEFRTTDG RKKAAAIMFD KRIFHLIVIG GDGSLMGAQK 120
  121 LKEEWGRFGE ELFAEGKITE EVANEGRELH LAGIVGSIDN DCIESDKSIG SDTALHRICE 180
  181 AIDGLVMTAQ SHQRVFVVEV MGRHCGYLAL TAAIAVEADY VFYPEIPPDE KWPEQLCHQL 240
  241 GSVRKMGKRQ NVIILGEGVT NSKGQRIDVR QVKEEIETRL QLEVRIATLG HLQRGGAPSF 300
  301 LDRLIGLRMG YEAVQEVLKG KEEKEGAVVT GQKTIAKVMC LRGHNIQRNE LSRVIRQTET 360
  361 ANEEIMQRHS DLACRLRGFG FLDKQTYLNF VSIPLSTTMP SRTKTFAVVH IGSPCAGMNA 420
  421 ATYSFTRMAN HSGIQVIGIK HGWDGLKNKD VKLLTWANVQ GWAQFGGSML GTKRQLPSEM 480
  481 DLIAEGLNSN NVDGLVIIGG FMAFESALIL QQNRSEYTCL SIPIVVIPAT ISNNCPGTCM 540
  541 SLGVDTALNE ICRQVDNISQ NAIGSKNKVM IIETMGSRSG FLATMTALST GSQFALIRQV 600
  601 ETNEKDLEKL AIETKERLDS GNLEKFLLIR SEGASDEIYS PDVKKIFDKV MKNKYGVRIT 660
  661 NLGYSQLGGH PSCFDRQMGI RMGVRAFEGI VNPVKMGDRD CCVIGLRGSS LRYVPVQGLG 720
  721 KKVCFEHGVP HNMWWLDLHP LVEAMTKKPQ EAVLSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..359] PSI-BLAST 108.0 ATP-dependent phosphofructokinase
    2 View Details [360..756] PSI-BLAST 74.045757 No description for 2higA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 6-phosphofructokinase activity
    		•  12.7403693686468 bayes_pls_golite062009
  • phosphofructokinase activity
    		•  11.7059647240147 bayes_pls_golite062009
  • fructose-6-phosphate binding
    		•  9.55959144901554 bayes_pls_golite062009
  • fructose binding
    		•  9.55841643584799 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  9.54757838113048 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.19280659830412 bayes_pls_golite062009
  • kinase activity
    		•  2.85624705588769 bayes_pls_golite062009
  • fructose-2,6-bisphosphate 2-phosphatase activity
    		•  2.7198911999025 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.67472251964197 bayes_pls_golite062009
  • sugar binding
    		•  2.21212411210899 bayes_pls_golite062009
  • monosaccharide binding
    		•  2.05358532613083 bayes_pls_golite062009
  • transferase activity
    		•  1.97789134877808 bayes_pls_golite062009
  • catalytic activity
    		•  1.89212073381079 bayes_pls_golite062009
  • protein binding
    		•  1.76136621968843 bayes_pls_golite062009
  • binding
    		•  1.57437723650762 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.97067862054315 bayes_pls_golite062009
  • hydrolase activity
    		•  0.276140444059183 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.184982121995695 bayes_pls_golite062009
  • tubulin binding
    		•  0.0889554716245424 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle