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Protein Overview: fkh-6

General Information:
Name(s) found: fkh-6 / CE03865 [WormBase]
Description(s) found:
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  • WBGene00001438 locus:fkh-6 status:Partially_confirmed UniProt:Q10924 protein_id:CCD61668.1 [WormBase]
  • pir||T15311 hypothetical protein B0286.5 - Caenorhabditis elegans [NCBI NR]
  • gi|17531283|ref|NP_494775.1| ForKHead transcription factor family member (fkh-6) [Caenorhabditis elegans] [NCBI NR]
  • gi|1053221|gb|AAA80692.1| Forkhead transcription factor family protein 6, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE03865 WBGene00001438 locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed TR:Q10924 protein_id:AAA80692.1 [wormpep150.fasta]
  • 03865 WBGene00001438 locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed TR:Q10924 protein_id:AAA80692.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ForKHead transcription factor family member (fkh-6) [Caenorhabditis elegans]gi|1053221|gb|AAA80692.1| Forkhead transcription factor family protein 6 [Caenorhabditis elegans]gi|7494837|pir||T15311 hypothetical protein B0286.5 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed TR:Q10924 protein_id:AAA80692.1 [wormpep115.fasta.reversed]
  • CE03865 fork head DNA-binding protein status:Predicted TR:Q10924 protein_id:AAA80692.1 [wormpep80.hongbin]
  • CE03865 WBGene00001438 locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed UniProt:Q10924_CAEEL protein_id:AAA80692.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE03865 WBGene00001438 locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed UniProt:Q10924_CAEEL protein_id:AAA80692.1| [wormORF-contam.fasta]
  • Forkhead transcription factor family protein 6 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • ForKHead transcription factor family member (fkh-6) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE03865 WBGene00001438 locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed UniProt:Q10924 protein_id:AAA80692.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE03865 WBGene00001438 locus:fkh-6 fork head DNA-binding protein status:Partially_confirmed UniProt:Q10924 protein_id:CCD61668.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE03865 WBGene00001438 locus:fkh-6 status:Partially_confirmed UniProt:Q10924 protein_id:CCD61668.1 [wormpep246-ecoli-contam.fasta]
  • ForKHead transcription factor family OS=Caenorhabditis elegans GN=fkh-6 PE=4 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IEALink to PubMed article]
    Biological Process: collagen and cuticulin-based cuticle attachment to epithelium [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    gonad development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    male germ-line sex determination [IMP]
    asymmetric cell division [IMP]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    regulation of transcription [ISSLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    transcription regulator activity [ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRHQTHLPF HIVQEGNSID KPPYSYVALI AMAIDASPDK RMTLNQIYKF IEAKFPYYRD  60
   61 ADAKRKQGWQ NSIRHNLSLN DCFVKKARDG QSCANDRKGN YWQMVADNAP QFDNGNFKRR 120
  121 RVKRLGIGKM GYANTTETTE TGTILQQQLP FFNGLKWPQN IQTMDPFQFF KFQYPNSITD 180
  181 SANTSQINNS SSSSSSFDTS IYTSAFPIPT SHFDTNLVAP SQPPPVVSDV EVVPSDTVKE 240
  241 EVLVDMKPLI PGISSTTFLT SLQMTDPRSI EQQQLLSTAS NMYPNAFMPP YTNWSCQPTT 300
  301 TFTGLSFDDP SLYGYGQQFP ASS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 37.0 Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
    2 View Details [128..323] MSA 8.465996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.85678231380989 bayes_pls_golite062009
  • transcription activator activity
    		•  3.70589483230587 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.58179858678904 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.2723726467408 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.96257232341735 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.322180400748724 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle