Protein Overview: let-23

General Information:
Name(s) found:	let-23 / CE03840 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00002299 locus:let-23 Receptor tyrosine-protein kinase let-23 status:Confirmed UniProt:P24348 protein_id:CAA93882.3 [WormBase] gi\|35210310\|emb\|CAA93882.3\| C. elegans protein ZK1067.1a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|25387062\|pir\|\|E88257 protein let-23 [imported] - Caenorhabditis elegans [NCBI NR] gi\|25146697\|ref\|NP_495962.2\| LEThal family member (let-23) [Caenorhabditis elegans] [NCBI NR] gi\|227422\|prf\|\|1703413A Tyr kinase [NCBI NR] gi\|110825728\|sp\|P24348.3\|LET23_CAEEL RecName: Full=Receptor tyrosine-protein kinase let-23; AltName: Full=Lethal protein 23; Flags: Precursor [NCBI NR] Receptor tyrosine-protein kinase let-23 OS=Caenorhabditis elegans GN=let-23 PE=1 SV=3 [Swiss-Prot] [wormpep67.fasta] CE03840 WBGene00002299 locus:let-23 tyrosine-protein kinase (Epidermal growth factor receptor subfamily) status:Confirmed SW:P24348 protein_id:CAA93882.3 [wormpep150.fasta] 03840 WBGene00002299 locus:let-23 tyrosine-protein kinase (Epidermal growth factor receptor subfamily) status:Confirmed SW:P24348 protein_id:CAA93882.3 [wormpep130-phg-ecoli-orf-rand.fasta] tyrosine kinase, LEThal LET-23 (150.5 kD) (let-23) [Caenorhabditis elegans]gi\|35210310\|emb\|CAA93882.3\| Hypothetical protein ZK1067.1 [Caenorhabditis elegans]gi\|25387062\|pir\|\|E88257 protein let-23 [imported] - Caenorhabditis elegansgi\|227422\|prf\|\|170341 [nrdb_11152004_Chlamydomonas] locus:let-23 tyrosine-protein kinase (Epidermal growth factor receptor subfamily) status:Confirmed TN:CAA93882 protein_id:CAA93882.3 [wormpep115.fasta.reversed] CE03840 WBGene00002299 locus:let-23 tyrosine-protein kinase (Epidermal growth factor receptor subfamily) status:Confirmed UniProt:P24348 protein_id:CAA93882.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE03840 WBGene00002299 locus:let-23 tyrosine-protein kinase (Epidermal growth factor receptor subfamily) status:Confirmed UniProt:P24348 protein_id:CAA93882.3\| [wormORF-contam.fasta] LEThal family member (let-23) [Caenorhabditis elegans] [nr-271106-contam.fasta] protein let-23 [imported] - Caenorhabditis elegans [nr-271106-contam.fasta] Receptor tyrosine-protein kinase let-23 precursor (Lethal protein 23) [nr-271106-contam.fasta] Tyr kinase [nr-271106-contam.fasta] Hypothetical protein ZK1067.1 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE03840 WBGene00002299 locus:let-23 status:Confirmed UniProt:P24348 protein_id:CAA93882.3 Receptor tyrosine-protein kinase let-23 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1323 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] membrane [IEA] basolateral plasma membrane [IDA]
Biological Process:	ovulation from ovarian follicle [IMP] positive regulation of vulval development [IMP] nematode larval development [IMP] male genitalia development [IMP] signal transduction [IEA] transmembrane receptor protein tyrosine kinase signaling pathway [IEA] protein amino acid phosphorylation [IEA]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [IEA] non-membrane spanning protein tyrosine kinase activity [IEA] transmembrane receptor protein tyrosine kinase activity [IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA] epidermal growth factor receptor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYPPSIGSI LLIIPIFLTF FGNSNAQLWK RCVSPQDCLC SGTTNGISRY GTGNILEDLE  60
   61 TMYRGCRRVY GNLEITWIEA NEIKKWREST NSTVDPKNED SPLKSINFFD NLEEIRGSLI 120
  121 IYRANIQKIS FPRLRVIYGD EVFHDNALYI HKNDKVHEVV MRELRVIRNG SVTIQDNPKM 180
  181 CYIGDKIDWK ELLYDPDVQK VETTNSHQHC YQNGKSMAKC HESCNDKCWG SGDNDCQRVY 240
  241 RSVCPKSCSQ CFYSNSTSSY ECCDSACLGG CTGHGPKNCI ACSKYELDGI CIETCPSRKI 300
  301 FNHKTGRLVF NPDGRYQNGN HCVKECPPEL LIENDVCVRH CSDGHHYDAT KDVRECEKCR 360
  361 SSSCPKICTV DGHLTNETLK NLEGCEQIDG HLIIEHAFTY EQLKVLETVK IVSEYITIVQ 420
  421 QNFYDLKFLK NLQIIEGRKL HNVRWALAIY QCDDLEELSL NSLKLIKTGA VLIMKNHRLC 480
  481 YVSKIDWSSI ITSKGKDNKP SLAIAENRDS KLCETEQRVC DKNCNKRGCW GKEPEDCLEC 540
  541 KTWKSVGTCV EKCDTKGFLR NQTSMKCERC SPECETCNGL GELDCLTCRH KTLYNSDFGN 600
  601 RMECVHDCPV SHFPTQKNVC EKCHPTCYDN GCTGPDSNLG YGGCKQCKYA VKYENDTIFC 660
  661 LQSSGMNNVC VENDLPNYYI STYDTEGVIE THCEKCSISC KTCSSAGRNV VQNKCVCKHV 720
  721 EYQPNPSERI CMDQCPVNSF MVPDTNNTVC KKCHHECDQN YHCANGQSTG CQKCKNFTVF 780
  781 KGDIAQCVSE CPKNLPFSNP ANGECLDYDI ASRQRKTRMV IIGSVLFGFA VMFLFILLVY 840
  841 WRCQRIGKKL KIAEMVDMPE LTPIDASVRP NMSRICLIPS SELQTKLDKK LGAGAFGTVF 900
  901 AGIYYPKRAK NVKIPVAIKV FQTDQSQTDE MLEEATNMFR LRHDNLLKII GFCMHDDGLK 960
  961 IVTIYRPLGN LQNFLKLHKE NLGAREQVLY CYQIASGMQY LEKQRVVHRD LATRNVLVKK1020
 1021 FNHVEITDFG LSKILKHDAD SITIKSGKVA IKWLAIEIFS KHCYTHASDV WAFGVTCWEI1080
 1081 ITFGQSPYQG MSTDSIHNFL KDGNRLSQPP NCSQDLYQEL LRCWMADPKS RPGFEILYER1140
 1141 FKEFCKVPQL FLENSNKISE SDLSAEERFQ TERIREMFDG NIDPQMYFDQ GSLPSMPSSP1200
 1201 TSMATFTIPH GDLMNRMQSV NSSRYKTEPF DYGSTAQEDN SYLIPKTKEV QQSAVLYTAV1260
 1261 TNEDGQTELS PSNGDYYNQP NTPSSSSGYY NEPHLKTKKP ETSEEAEAVQ YENEEVSQKE1320
 1321 TCL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: let-23

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: