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Protein Overview: nmt-1

General Information:
Name(s) found: nmt-1 / CE01406 [WormBase]
Description(s) found:
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  • WBGene00020549 locus:nmt-1 Probable glycylpeptide N-tetradecanoyltransferase status:Confirmed UniProt:P46548 protein_id:CCD63182.1 [WormBase]
  • gi|506799|gb|AAA19436.1| Hypothetical protein T17E9.2a [Caenorhabditis elegans] [NCBI NR]
  • pir||D88474 protein T17E9.2 [imported] - Caenorhabditis elegans [NCBI NR]
  • gi|17555118|ref|NP_498326.1| N-Myristoyl Transferase homolog family member (nmt-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|1171743|sp|P46548.1|NMT_CAEEL RecName: Full=Probable glycylpeptide N-tetradecanoyltransferase; AltName: Full=Peptide N-myristoyltransferase; AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase; Short=NMT [NCBI NR]
  • Probable glycylpeptide N-tetradecanoyltransferase OS=Caenorhabditis elegans GN=nmt-1 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE01406 WBGene00020549 status:Partially_confirmed SW:P46548 protein_id:AAA19436.1 [wormpep150.fasta]
  • 01406 WBGene00020549 status:Partially_confirmed SW:P46548 protein_id:AAA19436.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • n-myristoyltransferase (50.9 kD) (3H204) [Caenorhabditis elegans]gi|506799|gb|AAA19436.1| Hypothetical protein T17E9.2a [Caenorhabditis elegans]gi|25347704|pir||D88474 protein T17E9.2 [imported] - Caenorhabditis elegansgi|1171743|sp|P46548|NMT_CAEEL Pr [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed SW:P46548 protein_id:AAA19436.1 [wormpep115.fasta.reversed]
  • CE01406 status:Partially_confirmed SW:P46548 protein_id:AAA19436.1 [wormpep80.hongbin]
  • CE01406 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:P46548 protein_id:AAA19436.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE01406 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:P46548 protein_id:AAA19436.1| [wormORF-contam.fasta]
  • Hypothetical protein T17E9.2a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable glycylpeptide N-tetradecanoyltransferase (Peptide N-myristoyltransferase) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) [nr-271106-contam.fasta]
  • T17E9.2a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE01406 WBGene00020549 locus:nmt-1 status:Confirmed SW:P46548 protein_id:AAA19436.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE01406 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:P46548 protein_id:CCD63182.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE01406 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:P46548 protein_id:CCD63182.1 Probable glycylpeptide N-tetradecanoyltransferase [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 450 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    N-terminal protein myristoylation [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: glycylpeptide N-tetradecanoyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHGHSHDGA PCGGHHGDDG AGGSRPSVND VQALVDQLRL AGVDVSNMPN IPTAPRDMDE  60
   61 ARSKSFQFWS TQPVPQMDET VPADVNCAIE ENIALDKVRA EPFSLPAGFR WSNVDLSDEE 120
  121 QLNELYNLLT RNYVEDDDSM FRFDYSADFL KWALQVPGFR PEWHCGVRAD SNNRLLAFIG 180
  181 AVPQTVRVYD KTVNMVEINF LCVHKNLRSR RVAPVLIREI TRRVNVTGIF QAAFTAGIVI 240
  241 PKPVSVCRYY HRSLNPRKLI DVRFSHLSAK MTMARTIKLY KLPEETATRN LREMKSTDVP 300
  301 QVFKLLTTSL KQYSLAPVYN SEEELAHALV PKKGVVYSYV AENQNGKITD FVSFYSLPST 360
  361 VMGHTTHKTI YAAYLYYYVA GSVTPKQLIN DSLILANREK FDVFNALDLM HNEKIFSDLK 420
  421 FGKGDGNLQY YLYNWKCADM KPSQIGLVLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..450] PSI-BLAST 1000.0 Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • N-acyltransferase activity
    		•  5.20638659012287 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.84873027228137 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  4.76900479797874 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  4.76900479797874 bayes_pls_golite062009
  • acyltransferase activity
    		•  4.72881921515185 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.70793039001114 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  4.69837915971204 bayes_pls_golite062009
  • acetyltransferase activity
    		•  4.61906868269668 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  3.97737934696287 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  3.97737934696287 bayes_pls_golite062009
  • transferase activity
    		•  3.5778020729894 bayes_pls_golite062009
    		• 2.25529786324762 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.862184823552605 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.80295531895447 bayes_pls_golite062009
  • binding
    		•  0.585485465374786 bayes_pls_golite062009
  • transcription factor binding
    		•  0.19149008165837 bayes_pls_golite062009
  • protein binding
    		•  0.075825416385311 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle