YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: umps-1

General Information:
Name(s) found: umps-1 / CE00638 [WormBase]
Description(s) found:
Found 22 descriptions.
SHOW ALL
  • WBGene00011559 locus:umps-1 status:Confirmed UniProt:G5EDZ2 protein_id:CAA82579.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 497 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: 'de novo' pyrimidine base biosynthetic process [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    nucleoside metabolic process [IEALink to PubMed article]
    adenine salvage [IEALink to PubMed article]
    pyrimidine nucleotide biosynthetic process [IEALink to PubMed article]
    pyrimidine base biosynthetic process [IEALink to PubMed article]
    Molecular Function: adenine phosphoribosyltransferase activity [IEALink to PubMed article]
    orotidine-5'-phosphate decarboxylase activity [IEALink to PubMed article]
    transferase activity [IEALink to PubMed article]
    orotate phosphoribosyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLTDKTRN GALKRNLLRQ MLKASVFKFG EFQLKSGQIS PIYIDLRECF GHPGLLMLIS  60
   61 EAISKQVEIS EVQYAGVLGI PYAALPYASV AAGNYLKKPL LIVRKEAKSY GTKKLIEGLY 120
  121 QPNDRLILIE DVVTTGGSIL DVVKVLHTEN LVASDVFCIL DREQGGRQKL QDAGVTLHSL 180
  181 LDMQTVLTFL YSTGAIGDEQ WHGIVQALNL PYTSPTKLEI NSELENLSSL PYVENVRTPL 240
  241 AERESLTESA LIKKILGIMR RKKSNLCLAV DYTTVEQCLQ MIELAGPFVL AIKLHADAIT 300
  301 DFNEEFTRKL TTMANDMDFI IFEDRKFGDT GNTNLLQLTG AQKIANWADV VTVHAVQGSD 360
  361 SIAGVFRKLA KDPTYRLSGV LLIAQLSTKG SLTALEGYTE TAVKIANENR DVISGFITQT 420
  421 RVSACSDLLN WTPGVNLDAK SDSAGQQWRG VDEAIEVQQN DIIIVGRGVT SSSEPVQQLK 480
  481 RYRQIAWDAL TRSDDSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] PSI-BLAST 45.522879 Phosphoribosylpyrophosphate synthetase
    2 View Details [214..497] PSI-BLAST 73.69897 No description for 2eawA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • adenine phosphoribosyltransferase activity
    		•  3.1748712918814 bayes_pls_golite062009
  • uracil phosphoribosyltransferase activity
    		•  3.0470646511978 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  2.97347277288245 bayes_pls_golite062009
  • transferase activity
    		•  2.73727660668741 bayes_pls_golite062009
  • nucleobase binding
    		•  2.70671399975507 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.53679639481311 bayes_pls_golite062009
  • purine binding
    		•  2.50071119798576 bayes_pls_golite062009
  • catalytic activity
    		•  2.30431811394775 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.21367942706564 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  2.02298774328915 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.79779416554304 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.57737999906367 bayes_pls_golite062009
  • DNA binding
    		•  1.52807259795452 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.51875493459374 bayes_pls_golite062009
  • binding
    		•  1.28428238110443 bayes_pls_golite062009
  • amidophosphoribosyltransferase activity
    		•  0.932396739123353 bayes_pls_golite062009
  • transcription factor activity
    		•  0.899561328226456 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.749909396904601 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.429422054980564 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle