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Protein Overview: SPCC1840.08c

General Information:
Name(s) found: SPCC1840.08c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • protein disulfide isomerase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 561 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [ISSLink to PubMed article]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: ER-associated protein catabolic process [ISS]
    protein retention in ER lumen [ISSLink to PubMed article]
    Molecular Function: protein disulfide isomerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELGAWRSIL YIAFLFAITR HAFCKAVNLV HSPEGEEFEN ILSSVSATVE KKEVNNKLIM  60
   61 PTANRDNQGV REELLVSSFK ERKLLNTNSA NLRLNSIGSY EMIDFKQINS EFFLSHRQHG 120
  121 FVLFIDSKKK PRQSFYTDSA TSIVQLSKKY RNKIKFKSVD CASSLEKCEE IGINSFPSLV 180
  181 YYNNAGQKKV FTAHTPYEVL SKHADLITEL DETDGKVYPQ SIIRLEEFKN LKANEPVFFL 240
  241 YLHDYGSTPE DFDSLRIFAR YLVGFAPLYR TDDEKVIKTL NVTRLPHLVA IRHGVAFSYS 300
  301 ERSVSAMRNT FQLIKWASLL KYPLVPELTP AVVENLDSDS YLAIALINPT SQVKASKAIS 360
  361 TVQEIGLKWT LKLREVERKQ LLTAREKWWD HLRMLKQKGY DDVAFLAAEY SLPLPKNKKV 420
  421 TFVWVNSLQW KTWISHTFHI DPMGPSRFVL MDPSRMFYWD SSAKGLPLTL DDSSLILDTT 480
  481 FRVLAITGEG LPHEFSIPRG YVYLSEIKQY SSLILISLWI SLILFVSFLN RRLILHYSFE 540
  541 SVHQLKTLTR KFIYSSLLKQ D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] PSI-BLAST 8.0 NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
    2 View Details [97..561] PSI-BLAST 45.0 Crystal Structure of Yeast Protein Disulfide Isomerase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.00357390808173 bayes_pls_golite062009
  • protein binding
    		•  1.5095461875158 bayes_pls_golite062009
  • transporter activity
    		•  0.891062661562858 bayes_pls_golite062009
  • protein transporter activity
    		•  0.619500680502806 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.491842023249737 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.26936882742456 bayes_pls_golite062009
  • signal recognition particle binding
    		•  0.24222095802271 bayes_pls_golite062009
  • heat shock protein binding
    		•  0.162050450070629 bayes_pls_golite062009
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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