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View Structure Prediction Details

Protein: SPCC1840.08c
Organism: Schizosaccharomyces pombe
Length: 561 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC1840.08c.

Description E-value Query
Range
Subject
Range
gi|74000349 - gi|74000349|ref|XP_535453.2| PREDICTED: similar to protein disulfide isomerase-associated 3 precurso...
270.0 [0..102] [498..209]
gi|39975797, gi|... - gi|39975797|ref|XP_369289.1| hypothetical protein MG06175.4 [Magnaporthe grisea 70-15], gb|EAA53047....
255.0 [0..18] [489..166]
gi|112180560 - gi|112180560|gb|AAH36000.3| PDIA3 protein [Homo sapiens]
252.0 [0..102] [498..61]
gi|114670980 - gi|114670980|ref|XP_001164327.1| PREDICTED: prolyl 4-hydroxylase, beta subunit isoform 5 [Pan troglo...
251.0 [0..101] [498..25]
gi|60653955, gi|... - gi|60653957|gb|AAX29671.1| glucose regulated protein 58kDa [synthetic construct], gi|60653955|gb|AAX...
246.0 [0..102] [498..27]
PDIA3_CHICK - Protein disulfide-isomerase A3 OS=Gallus gallus GN=PDIA3 PE=2 SV=1
245.0 [0..102] [498..27]
PDIA3_CHLAE - Protein disulfide-isomerase A3 OS=Chlorocebus aethiops GN=PDIA3 PE=2 SV=1
gi|163781048 - gi|163781048|gb|ABY40815.1| protein disulfide isomerase family A, member 3 (predicted) [Papio anubis...
gi|109080868, gi... - gi|109080870|ref|XP_001109119.1| PREDICTED: similar to protein disulfide isomerase-associated 3 prec...
245.0 [0..102] [498..27]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELGAWRSIL YIAFLFAITR HAFCKAVNLV HSPEGEEFEN ILSSVSATVE KKEVNNKLIM  60
   61 PTANRDNQGV REELLVSSFK ERKLLNTNSA NLRLNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1xblA
Description: NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.00357390808173 bayes_pls_golite062009
protein binding 1.5095461875158 bayes_pls_golite062009
transporter activity 0.891062661562858 bayes_pls_golite062009
protein transporter activity 0.619500680502806 bayes_pls_golite062009
substrate-specific transporter activity 0.491842023249737 bayes_pls_golite062009
unfolded protein binding 0.26936882742456 bayes_pls_golite062009
signal recognition particle binding 0.24222095802271 bayes_pls_golite062009
heat shock protein binding 0.162050450070629 bayes_pls_golite062009
catalytic activity 0.106988907594358 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [97-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGSYEMIDFK QINSEFFLSH RQHGFVLFID SKKKPRQSFY TDSATSIVQL SKKYRNKIKF  60
   61 KSVDCASSLE KCEEIGINSF PSLVYYNNAG QKKVFTAHTP YEVLSKHADL ITELDETDGK 120
  121 VYPQSIIRLE EFKNLKANEP VFFLYLHDYG STPEDFDSLR IFARYLVGFA PLYRTDDEKV 180
  181 IKTLNVTRLP HLVAIRHGVA FSYSERSVSA MRNTFQLIKW ASLLKYPLVP ELTPAVVENL 240
  241 DSDSYLAIAL INPTSQVKAS KAISTVQEIG LKWTLKLREV ERKQLLTARE KWWDHLRMLK 300
  301 QKGYDDVAFL AAEYSLPLPK NKKVTFVWVN SLQWKTWISH TFHIDPMGPS RFVLMDPSRM 360
  361 FYWDSSAKGL PLTLDDSSLI LDTTFRVLAI TGEGLPHEFS IPRGYVYLSE IKQYSSLILI 420
  421 SLWISLILFV SFLNRRLILH YSFESVHQLK TLTRKFIYSS LLKQD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 2b5eA
Description: Crystal Structure of Yeast Protein Disulfide Isomerase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle