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Protein Overview: SPBC800.10c

General Information:
Name(s) found: SPBC800.10c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • EPS15 repeat family actin cortical patch component [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1116 amino acids

    Gene Ontology:
    Cellular Component: cell cortex [IDALink to PubMed article]
    actin cortical patch [ISSLink to PubMed article]
    Biological Process: endocytosis [ISSLink to PubMed article]
    intracellular protein transport [ICLink to PubMed article]
    actin cortical patch assembly [ISSLink to PubMed article]
    receptor-mediated endocytosis [ISSLink to PubMed article]
    Molecular Function: calcium ion binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNLSAEEQ TAFDQLFKIA DKQDIGVITG EEAVPFLEKS GLAPQVLGQI WQIADAENRG  60
   61 FLTFSGFVIA MRLVALAQEK LPFDYKKSGK IPYFADIHIS GVDSSKFVQL NRPNNVSSGD 120
  121 GSDGSFLPPI SSDEMTRYQQ MFTTVCPTDG LMDGDRASSI FGRAPLSTEI LARVWNLVDT 180
  181 HKRGALDIRE FNTGMHIINL LLNGSLKSPP VSISPSFIAS AASTSSVSAP SQYPGLSRSP 240
  241 PVQAPNIPVS DPWAIPSQDL TSFCQLFSNV DKAHKGYVSG SEAYSFFLAS KLPEDVLAQI 300
  301 WDLSDTNSNG KLNIGEFCIS LYLIKLKLSG KELPKVLPSS MLSSVAPLMQ KSKSVPTSIP 360
  361 SVVPANISSP NPNPTLAPNP TGPSRVTSGT EDLLSLDATP FSPTLAPQHT SSNATKHSAP 420
  421 PVTKSAPFPV VSPLQLNHTP GFPTSPAAKP NSPTSTFFPQ SSFGQTIAKN TMDKPSAVRT 480
  481 SVPSQLAAPI PQVASAEQLK LAAEVPKLES QLSQVKKSND DLQKSSRDVA ANLSDVKAKV 540
  541 SEIRKAYDEE LAKAKQISLD IETNKAQTEQ VNREYSILEA TLNALQKQNK QKGEVLEQVV 600
  601 AESEAAKNMV ESSNASIQQL KSEVADKEQT LAQLHLQLDE MTQRLVSLDE ESKAVSQRKL 660
  661 DLEYKINNSK TQLATATEEY HEHSKQLEAE KQELSKLEDG LKSVNLTEEA PKPEVDSTPR 720
  721 FPSFTSNGIT TDKPTLPDTT SSVPTQHNSF DAMHNTLRSP SLNSNNSSAH ASTVSRNPFH 780
  781 NLKISGASSP VSNFWESEFA SAVFPRSISK TTSLSVNNSS VNPSLDSEPV QLSNMEEPQH 840
  841 QDSSVVDVST SASQRGSPVL SDLSKLTGSA RNTAEPVENT SAEPIENTSA PTPFEIANKQ 900
  901 QATEPISAPF ATETISTPAP VKPPVPPSRR DRSAQDGVVQ QATPHIQDEF PPIQFNEIDD 960
  961 DESSSDEEPP MSNLSPQISI GSVTNYTSAV TELPDPNHQL EMSTTTHVQH PNSETIPSST1020
 1021 ENQYFDTTSG AFEANSNTEV TVNSNEVSQP FDFDTANESD NDDDELPVQQ VVSGSLANDA1080
 1081 FNVDDEFDNQ FANLQAAEIK DDDNSSTDEE EHAGHH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] PSI-BLAST 27.69897 Pob1
    2 View Details [85..361] FFAS03 3.42 Structure of the Arabidopsis thaliana SOS3 complexed with Calcium(II) and Manganese(II) ions
    3 View Details [362..770] PSI-BLAST 28.30103 Heavy meromyosin subfragment
    4 View Details [771..855] PSI-BLAST 5.0 No description for 2i1jA was found.
    5 View Details [856..1116] PSI-BLAST 3.522879 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  3.96919556235483 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.49668552859347 bayes_pls_golite062009
  • structural constituent of muscle
    		•  3.12414907235012 bayes_pls_golite062009
  • microfilament motor activity
    		•  2.9702957313812 bayes_pls_golite062009
  • binding
    		•  2.59835122922082 bayes_pls_golite062009
  • motor activity
    		•  2.57627414053278 bayes_pls_golite062009
  • actin filament binding
    		•  2.35534489389161 bayes_pls_golite062009
  • myosin binding
    		•  2.34125070430971 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.06646671333275 bayes_pls_golite062009
  • calcium ion binding
    		•  1.75413488311654 bayes_pls_golite062009
  • protein binding
    		•  1.36984860219682 bayes_pls_golite062009
  • metal ion binding
    		•  1.19984728454368 bayes_pls_golite062009
  • cation binding
    		•  1.19984728454368 bayes_pls_golite062009
  • ion binding
    		•  1.1923653453763 bayes_pls_golite062009
  • actin monomer binding
    		•  0.9954841049256 bayes_pls_golite062009
  • tubulin binding
    		•  0.710693016758742 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.61866037435065 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.401233649632102 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.341013054040087 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.32485782650283 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.324368071436317 bayes_pls_golite062009
  • microtubule binding
    		•  0.278596514315141 bayes_pls_golite062009
  • structural molecule activity
    		•  0.234626449126289 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.116648335890738 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle