YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC800.10c
Organism:	Schizosaccharomyces pombe
Length:	1116 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC800.10c.

Description	E-value	Query Range	Subject Range
gi\|68388302 - gi\|68388302\|ref\|XP_696268.1\| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]	338.0	[0..305]	[1112..1711]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1	278.0	[0..304]	[1113..718]
MYH2_HORSE - Myosin-2 OS=Equus caballus GN=MYH2 PE=2 SV=1	276.0	[0..304]	[1113..718]
MYH4_MOUSE - Myosin-4 OS=Mus musculus GN=Myh4 PE=2 SV=1	276.0	[0..304]	[1113..720]
gi\|165973992, gi... - gi\|83026762\|gb\|ABB96408.1\| fast myosin heavy chain 2X [Canis familiaris], gi\|165973992\|ref\|NP_001107...	276.0	[0..304]	[1113..734]
gi\|42476190, gi\|... - gi\|42476190\|ref\|NP_060004.2\| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens], gi\|...	276.0	[0..304]	[1113..722]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNLSAEEQ TAFDQLFKIA DKQDIGVITG EEAVPFLEKS GLAPQVLGQI WQIADAENRG  60
   61 FLTFSGFVIA MRLVALAQEK LPFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.69897
Match:	1iq3A
Description:	Pob1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	3.96919556235483	bayes_pls_golite062009
cytoskeletal protein binding	3.49668552859347	bayes_pls_golite062009
structural constituent of muscle	3.12414907235012	bayes_pls_golite062009
microfilament motor activity	2.9702957313812	bayes_pls_golite062009
binding	2.59835122922082	bayes_pls_golite062009
motor activity	2.57627414053278	bayes_pls_golite062009
actin filament binding	2.35534489389161	bayes_pls_golite062009
myosin binding	2.34125070430971	bayes_pls_golite062009
actin-dependent ATPase activity	2.06646671333275	bayes_pls_golite062009
calcium ion binding	1.75413488311654	bayes_pls_golite062009
protein binding	1.36984860219682	bayes_pls_golite062009
metal ion binding	1.19984728454368	bayes_pls_golite062009
cation binding	1.19984728454368	bayes_pls_golite062009
ion binding	1.1923653453763	bayes_pls_golite062009
actin monomer binding	0.9954841049256	bayes_pls_golite062009
tubulin binding	0.710693016758742	bayes_pls_golite062009
myosin heavy chain binding	0.61866037435065	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.401233649632102	bayes_pls_golite062009
pyrophosphatase activity	0.341013054040087	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.32485782650283	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.324368071436317	bayes_pls_golite062009
microtubule binding	0.278596514315141	bayes_pls_golite062009
structural molecule activity	0.234626449126289	bayes_pls_golite062009
structural constituent of cytoskeleton	0.116648335890738	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [85-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKKSGKIPYF ADIHISGVDS SKFVQLNRPN NVSSGDGSDG SFLPPISSDE MTRYQQMFTT  60
   61 VCPTDGLMDG DRASSIFGRA PLSTEILARV WNLVDTHKRG ALDIREFNTG MHIINLLLNG 120
  121 SLKSPPVSIS PSFIASAAST SSVSAPSQYP GLSRSPPVQA PNIPVSDPWA IPSQDLTSFC 180
  181 QLFSNVDKAH KGYVSGSEAY SFFLASKLPE DVLAQIWDLS DTNSNGKLNI GEFCISLYLI 240
  241 KLKLSGKELP KVLPSSMLSS VAPLMQKSKS VPTSIPS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.42
Match:	1v1fA
Description:	Structure of the Arabidopsis thaliana SOS3 complexed with Calcium(II) and Manganese(II) ions
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [362-770]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVPANISSPN PNPTLAPNPT GPSRVTSGTE DLLSLDATPF SPTLAPQHTS SNATKHSAPP  60
   61 VTKSAPFPVV SPLQLNHTPG FPTSPAAKPN SPTSTFFPQS SFGQTIAKNT MDKPSAVRTS 120
  121 VPSQLAAPIP QVASAEQLKL AAEVPKLESQ LSQVKKSNDD LQKSSRDVAA NLSDVKAKVS 180
  181 EIRKAYDEEL AKAKQISLDI ETNKAQTEQV NREYSILEAT LNALQKQNKQ KGEVLEQVVA 240
  241 ESEAAKNMVE SSNASIQQLK SEVADKEQTL AQLHLQLDEM TQRLVSLDEE SKAVSQRKLD 300
  301 LEYKINNSKT QLATATEEYH EHSKQLEAEK QELSKLEDGL KSVNLTEEAP KPEVDSTPRF 360
  361 PSFTSNGITT DKPTLPDTTS SVPTQHNSFD AMHNTLRSPS LNSNNSSAH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.30103
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [771-855]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASTVSRNPFH NLKISGASSP VSNFWESEFA SAVFPRSISK TTSLSVNNSS VNPSLDSEPV  60
   61 QLSNMEEPQH QDSSVVDVST SASQR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.0
Match:	2i1jA
Description:	No description for 2i1jA was found.

Predicted Domain #5

Region A:
Residues: [856-1116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSPVLSDLSK LTGSARNTAE PVENTSAEPI ENTSAPTPFE IANKQQATEP ISAPFATETI  60
   61 STPAPVKPPV PPSRRDRSAQ DGVVQQATPH IQDEFPPIQF NEIDDDESSS DEEPPMSNLS 120
  121 PQISIGSVTN YTSAVTELPD PNHQLEMSTT THVQHPNSET IPSSTENQYF DTTSGAFEAN 180
  181 SNTEVTVNSN EVSQPFDFDT ANESDNDDDE LPVQQVVSGS LANDAFNVDD EFDNQFANLQ 240
  241 AAEIKDDDNS STDEEEHAGH H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1c1gA
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: