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Protein Overview: rga7

General Information:
Name(s) found: rga7 / SPBC23G7.08c [Sanger Pombe]
Description(s) found:
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  • pir||T39954 probable gtpase activating protein homolog - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|62287344|sp|O94466.1|RGA7_SCHPO RecName: Full=Probable Rho-GTPase-activating protein 7 [NCBI NR]
  • gi|4106685|emb|CAA22624.1| Rho-type GTPase activating protein Rga7 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112658|ref|NP_595866.1| GTPase activating protein Rga7 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • GTPase activating protein Rga7 [Sanger Pombe]
  • Probable Rho-GTPase-activating protein 7 OS=Schizosaccharomyces pombe GN=rga7 PE=1 SV=1 [Swiss-Prot]
  • GTPASE ACTIVATOR; RHOGAP DOMAIN; SIMILAR TO S. CEREVISIAE RGD1: O94466; [pompepVF.fasta]
  • PUTATIVE GTPASE ACTIVATING PROTEIN HOMOLOG: O94466; [pompepV13]
  • Putative GTPase activating protein homolog [pompep4896]
  • |rga7||GTPase activator [pompepnew.fasta]
  • Rga7 protein (Spbc23g7.08c protein) [4896.FASTAC]
  • |rga7||GTPase activating protein|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative gtpase activating protein homolog [Schizosaccharomyces pombe]gi|4106685|emb|CAA22624.1| SPBC23G7.08c [Schizosaccharomyces pombe]gi|7492628|pir||T39954 probable gtpase activating protein homolog - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O94466) Putative GTPase activating protein homolog [pompep4896_normal_reversed]
  • |rga7||Rho-type GTPase activating protein Rga7|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Probable Rho-GTPase-activating protein 7 [nr-271106-contam.fasta]
  • SPBC23G7.08c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC23G7.08c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Probable Rho-GTPase-activating protein 7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rga7 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 695 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    actin cortical patch [ISSLink to PubMed article]
    Biological Process: regulation of Rho GTPase activity [ISS]
    actin cytoskeleton organization [ISSLink to PubMed article]
    Molecular Function: Rho GTPase activator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSAPSSSTT PASPPTSPPN TTSSDDFAVL KEPKVEAILN SELGLAILND RIKDYLLTCK  60
   61 ELAGFFKKRS ILEEESGKNL QKLAKSYLET FQSKHHSPQS FSASVITSME IHEQLANHSL 120
  121 TLQKTLSAFS DQVIEFHKNA ERKRKSIKEY AKKQENAYLE AVMQMDKSKS RFKGAETEYN 180
  181 RALDNKNTGD SQKKVGFFKP KSNAQLTKLE DEARLKAENA ESDMHSKIEN AQNVQKQLLC 240
  241 IHRPNYIKQF FSLQREIESS LIANYLRYTK LCESNTLLNG LTIRPQKPTP TNCGLQHALD 300
  301 NINANTDFVQ YVLHASIKHE DNKNPTDASK TKIIQPPSSY GTGSSAGKTN PPVNPTIKVT 360
  361 AAIPSPLQNT NPAPSTFPNP SVASPAFPNS STSNPSTAPA SASPLASTLK PSTANDTNGS 420
  421 SSSSSSNPRT SSPLASNAEN KPPVAQQSPP VLLPTLPPIQ TTTIQTSREV APPPSSINSN 480
  481 RAASPFRPTS VSPQPSSPTK SLLFGARLDA IILREHSNIP NIVMQCTSQV ENFGLNLQGI 540
  541 YRVPSSSARV NMLRSQFENN PLLQLHTPED YENDVHAVAD LLKIFFRELR EPLIPDNHQR 600
  601 DFIDAGNVED ESRRRDAVHR AINDLPDANY STIRHLTIHL AKIKENSDVN KMSTNNLAII 660
  661 WGPTIIKQAT IPEISSFSRT IEILIDYCFT IFDYD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..345] PSI-BLAST 17.30103 No description for 2eflA was found.
    2 View Details [346..695] PSI-BLAST 53.0 Crystal Structure of the Human Beta2-Chimaerin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  2.86582611923959 bayes_pls_golite062009
  • binding
    		•  2.43584893484993 bayes_pls_golite062009
  • protein binding
    		•  1.87308005875135 bayes_pls_golite062009
  • identical protein binding
    		•  0.909409198394921 bayes_pls_golite062009
  • enzyme binding
    		•  0.58709209959999 bayes_pls_golite062009
  • GTPase binding
    		•  0.50066793947946 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.459881864914566 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.456472132383968 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.180886944097381 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0531578648468707 bayes_pls_golite062009
    2
    Term Confidence Notes
  • Rho GTPase activator activity
    		•  4.58620967349979 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  4.48279904625182 bayes_pls_golite062009
  • actin binding
    		•  4.17357159737697 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.42802398019084 bayes_pls_golite062009
  • microfilament motor activity
    		•  2.96155001519594 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.70614727793157 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.68579854252375 bayes_pls_golite062009
  • actin filament binding
    		•  2.45667344398622 bayes_pls_golite062009
  • binding
    		•  2.36195429973813 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  2.06038764955701 bayes_pls_golite062009
  • motor activity
    		•  2.04743766323523 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.9750017471254 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.95738547986197 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  1.74529419104576 bayes_pls_golite062009
  • tubulin binding
    		•  1.56332747753627 bayes_pls_golite062009
  • protein binding
    		•  1.29100556128076 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.09070479183477 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  0.967362611034944 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  0.958295643211986 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  0.847021935833721 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.717730683557543 bayes_pls_golite062009
  • microtubule binding
    		•  0.648232426961013 bayes_pls_golite062009
  • diacylglycerol binding
    		•  0.61310450668925 bayes_pls_golite062009
  • ADP binding
    		•  0.56346827542888 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.36751853312336 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.348246993470003 bayes_pls_golite062009
  • Rho GTPase binding
    		•  0.33949271618205 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.298334474872045 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle