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Protein Overview: vps8

General Information:
Name(s) found: vps8 / SPAC17A2.06c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • WD repeat protein Vps8 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1272 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    CORVET complex [ISS]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: late endosome to vacuole transport [ISSLink to PubMed article]
    intracellular protein transport [RCALink to PubMed article]
    protein ubiquitination [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSKYGRSSL KIKNGDDTRT LRALSFSKDS VNSSSFDNEA ASTTLGISTA IHASNRPFRQ  60
   61 DEYSWNDCWM RWGQLRRVSS QLRELRFTMN DQPATVTSIA YQGTLLVAGT SSGHVLLNDW 120
  121 RTNDFQILKP GLSSNESVTL PVTSLAISNS KRIVCQGHAG GIIFVWDVSR KPPLQLFTIN 180
  181 QHSEDSVLTH LVFNGNSDDV LLSTDHLGKI AVHEFYNLVI NKHCTSWNLD MSKSNSLNLD 240
  241 SIIVDTSSIS FEELHITGVK HFSFVVLQSL QSIQIVTLFP KTTLIYEFKY PAGIVSSACH 300
  301 SFSSSIVHKN GENTKLHAFF ATAYNNNLRL YSVTFHKGYM SLQLMDRKKF AKAIWKLWWF 360
  361 PSSSIIIILF DDMELAFVNS MSLDIIGTST ILDKSLLRWD WYSNSLAAIG VSQTVFPFIS 420
  421 SSLCISPRYM FVVNSETVSV GSFLMVSEQL QMLSERYGFF DSIKFGSYCV SNLSIFPKLL 480
  481 LEKTSVINLI MALYVKLLKS LARDFPARSP FEATSQKTND YELEVQHLFT WTCELYSENF 540
  541 NTVISSFIIA NSLGILPEII EQIIPVFTRV GKVYVVLEAL FDLILSQRFT NPSPQLQHHI 600
  601 LNYLNDCKRL QDMDKLIPCI EYQSLDLDFI TKFSRSKGLF DSLCYVSIYA FNDYSIPLVQ 660
  661 FLNLLKSDID SPSEETSINV EKGFHFLLYS LTGMKYPLGH SNNINDAYVV IHTLLKVIFS 720
  721 VVPLPFDVPV DNSVDFPYLR LFLEKHADDF FRCLEVAFDY PYFSLEKVTI AKKLLDTVNR 780
  781 QWILECISQL YEKKKSVSQS YYIFVSHVTA NYSNQLLFSQ SFYQGILDGL CNIDVPDDKR 840
  841 EVVEAAIEEL LTVYEHFDIA TTLLSCWDHQ LYQVILHISF KCGRYEDYIE AILALWKQKG 900
  901 QKHSFVSESS EALISLVFNN LQTINRFPGH RERYVSTLIS HCGDLFAINH VCFVRNSLKY 960
  961 LLDDFTKVIT KTFSIKSIRL QFLSLIIYEI TYEQLSSWYR ERTILSFLEL VSFDQGDVKM1020
 1021 LELLRLHPKL VRLQGLMEIL NKNDCIESCI FVYRELAEYK LALSHVSKYI EKSMSVFDLE1080
 1081 KSDDMTSRRI ERLCLHLKTV VPLFEQCTKE VSAEDVTNFW LELVFTLLLV YIKLSLKGSI1140
 1141 NSQITFKDFQ QELSLCIENL LDSFLSKTNS YKIALNTVLV RICEEASRNE HSDQYLRKLL1200
 1201 LKLITDLYIN HDITKECFLL WDMKQFYEIR STLLQNASGV LVEDPKLQKN AKGQYTSKLK1260
 1261 VYFSGLIERE DL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..541] PSI-BLAST 45.39794 Actin interacting protein 1
    2 View Details [542..694] deduced N/A No confident structure predictions are available.
    3 View Details [695..811] deduced N/A No confident structure predictions are available.
    4 View Details [812..1169] PSI-BLAST 4.69897 Clathrin D6 Coat
    5 View Details [1170..1272] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  2.77599521858855 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.52062758665339 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.6726520555114 bayes_pls_golite062009
  • protein binding
    		•  1.61720914342874 bayes_pls_golite062009
  • binding
    		•  1.40353148474598 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.734230328744066 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.110806113669931 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.46

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle