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Protein Overview: SPAC6F6.12

General Information:
Name(s) found: SPAC6F6.12 [Sanger Pombe]
Description(s) found:
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  • pir||T39046 hypothetical phoX domain containing protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|59800468|sp|O14243.3|SNX4_SCHPO RecName: Full=Sorting nexin-4; AltName: Full=Autophagy-related protein 24 [NCBI NR]
  • gi|2389002|emb|CAB11735.1| autophagy associated protein Atg24 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114817|ref|NP_593905.1| autophagy associated protein Atg24 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • autophagy associated protein Atg24 [Sanger Pombe]
  • Sorting nexin-4 OS=Schizosaccharomyces pombe GN=snx4 PE=1 SV=3 [Swiss-Prot]
  • PUTATIVE NEXIN SORTING PROTEIN; POSSIBLY INVOLVED IN PROTEASOME FUNCTION BY SIMILAR TO S. CEREVISIAE SNX4; PX DOMAIN PROTEIN: O14243;P78806; [pompepVF.fasta]
  • PUTATIVE NEXIN SORTING PROTEIN; POSSIBLY INVOLVED IN PROTEASOME FUNCTION BY SIMILARITY TO YEAST SNX4; PX DOMAIN PROTEIN: O14243;P78806; [pompepV13]
  • Hypothetical 46.4 kDa protein C6F6.12 in chromosome I [pompep4896]
  • |||putative nexin sorting protein [pompepnew.fasta]
  • |||involved in proteasome function (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • Putative nexin sorting protein; possibly involved in proteasome function by similarity to yeast snx4; pX domain protein [Schizosaccharomyces pombe]gi|2389002|emb|CAB11735.1| SPAC6F6.12 [Schizosaccharomyces pombe]gi|7490728|pir||T39046 hypothetical phoX [nrdb_11152004_Chlamydomonas]
  • |||PX domain protein|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O14243) Hypothetical 46.4 kDa protein C6F6.12 in chromosome I [pompep4896_normal_reversed]
  • |||autophagy associated protein Atg24 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC6F6.12 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Sorting nexin-4 (Autophagy-related protein 24) [nr-271106-contam.fasta]
  • hypothetical protein SPAC6F6.12 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Sorting nexin-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=snx4 PE=1 SV=3 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 401 amino acids

    Gene Ontology:
    Cellular Component: endosome [IEA]
    cytoplasm [ISSLink to PubMed article]
    pre-autophagosomal structure [ISSLink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    extrinsic to membrane [IEA]
    autophagic vacuole [ISSLink to PubMed article]
    Biological Process: piecemeal microautophagy of nucleus [ISS]
    early endosome to Golgi transport [ISS]
    protein targeting to vacuole [ISSLink to PubMed article]
    CVT pathway [ISS]
    Molecular Function: phosphatidylinositol-3-phosphate binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSVNLDEP STNSTHFLQC LVTEPRKELQ GSRDTHVSYL IITKTNLSIF TRAECKVRRR  60
   61 FSDFVKLQEI LSRMNEDCVV PPLPAKHKLE YIKGGRFSDN FINRRAKLLN RYITRCALHP 120
  121 VLHQSPHFIA FLENPNWNNY VRFFIQPKLN NTSKLDEISD SLLNAFSKLK EEPTEFDIQR 180
  181 DHVQQFMFGI SNLEGSIQKL LRLEKALESD YEDVSIQFDR LASLDQALDV PIESIQNALQ 240
  241 QTGTEYANLT EKLTLLLDTI KDVESYAHSL KELLKRRDQK QQDVEALQEY SAKLSLERDK 300
  301 ISSGGSNGFS LSKTLDDLRG IDHNDTRLKR LEHVQSELQA VEQAIQEASA VHDAFNQRVR 360
  361 EESKLFDSVR QSEMLSAISD YANVHVEFFT NIRDLWIRVK Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] FFAS03 1.42 Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.
    2 View Details [75..401] PSI-BLAST 5.045757 No description for 2dfsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle