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The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment. The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. Degradation of a cell nucleus by microautophagy. The infolding of a membrane, resulting in formation of a vesicle. The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: piecemeal microautophagy of nucleus
Acc: GO:0034727
Aspect: Biological Process
Desc: Degradation of a cell nucleus by microautophagy.
Synonyms:
  • PMN
Proteins in PDR annotated with:
   This term: 21 [Search]
   Term or descendants: 22 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034727 - piecemeal microautophagy of nucleus (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle