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Protein Overview: seb1

General Information:
Name(s) found: seb1 / SPAC222.09 [Sanger Pombe]
Description(s) found:
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  • gi|6433994|emb|CAB60701.1| RNA-binding protein Seb1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|59800224|sp|Q9UTE3.3|SEB1_SCHPO RecName: Full=Rpb7-binding protein seb1 [NCBI NR]
  • gi|19114060|ref|NP_593148.1| RNA-binding protein Seb1 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • pir||T50150 yeast nrd1-like protein [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • RNA-binding protein Seb1 [Sanger Pombe]
  • Rpb7-binding protein seb1 OS=Schizosaccharomyces pombe GN=seb1 PE=1 SV=3 [Swiss-Prot]
  • POSSIBLY CONTROLS TRANSCRIPTIONAL ELONGATION, INTERACTS WITH THE C-TERMINAL DOMAIN OF RNA POLYMERASE II LARGE SUBUNIT AND BINDS DNA THROUGH A RNA RECOGNITION (RRM) DOMAIN; SIMILAR TO S. CEREVISIAE NRD1: O74176;Q9UTE3;Q9UTX2; [pompepVF.fasta]
  • PUTATIVE PROTEIN THAT CONTROLS TRANSCRIPTIONAL ELONGATION, INTERACTS WITH THE C-TERMINAL DOMAIN OF RNA POLYMERASE II LARGE SUBUNIT AND BINDS DNA THROUGH A RNA RECOGNITION (RRM) DOMAIN; BY SIMILARITY TO YEAST NRD1: O74176;Q9UTE3;Q9UTX2; [pompepV13]
  • Hypothetical 66.4 kDa protein C222.09 in chromosome I [pompep4896]
  • |||possibly involved in the regulation of transcriptional elongation [pompepnew.fasta]
  • |seb1||involved in RNA elongation from Pol II promoter (regulation) (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • yeast nrd1-like protein [Schizosaccharomyces pombe]gi|6433994|emb|CAB60701.1| SPAC222.09 [Schizosaccharomyces pombe]gi|11286212|pir||T50150 yeast nrd1-like protein [imported] - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |seb1||RNA-binding protein involved in processing of transcripts |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (Q9UTE3) Hypothetical 66.4 kDa protein C222.09 in chromosome I [pompep4896_normal_reversed]
  • |seb1||RNA-binding protein Seb1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Rpb7-binding protein seb1 [nr-271106-contam.fasta]
  • SPAC222.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC222.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Rpb7-binding protein seb1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=seb1 PE=1 SV=3 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 620 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: termination of RNA polymerase II transcription, poly(A)-independent [ISSLink to PubMed article]
    RNA 3'-end processing [ISSLink to PubMed article]
    Molecular Function: RNA binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIAEFDGI LDSLEHSKTG ISGSKILKLT NLSMENVSEN AQFVASVYKY AKRAPVTHKL  60
   61 GALYILDSIV RSFQDGAKKN NESFENPVDA SFSGGWCKAA EITDSLVADA IQHAPSAHLP 120
  121 KILKLCDIWE KASTFPPEKL ESLRSKLKDA MASTEPVSVD SAAAPSQSTN PEGNGGSVGS 180
  181 QAAAPTSRPV ENDAASILEA LAAFAQKAPV PSAAEESVST PPQPAVAPSV SAVVPNLPVH 240
  241 PATAINAQSQ SGNPLSNPLF QPSNVPQSIP SGPMGMKTGS VNDTQSQQIT LMNVLASQNV 300
  301 PPAQIDSIMK AAFPNYNAPF QPAGVGSVPL PAPTSSQSLR LGSLHRSRSP SPRSGRPRRS 360
  361 PSPSHLSIPS TLPPADGVPK PTPDGFPRRF ERDPTIPPDS IKVYSRTLFL GGITRSVREP 420
  421 VLRSMFERFG SVQSLILNHN YRHGFLKMFR RDAAEKAQVA MENVPFADTT IRTKWGVGFG 480
  481 PRECSDFSTG ISVIPIRLLT DADRTWLVTA EYGGTGGLPI TPGIALDEPD IEIGLGISSK 540
  541 AISKRGKDFA MRRDERFRGR KPYRGGPPIH HGERHFDSGN DWHGNPSTVP PPTNPYNPGY 600
  601 PYMDPNYSSG YVSQPPWQPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..207] PSI-BLAST 35.154902 No description for 2diwA was found.
    2 View Details [208..272] deduced N/A No confident structure predictions are available.
    3 View Details [273..398] PSI-BLAST 25.0 Poly(A)-binding protein
    4 View Details [399..620] PSI-BLAST 30.0 Sex-lethal protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleic acid binding
    		•  4.50398990564944 bayes_pls_golite062009
  • RNA binding
    		•  4.46119712758726 bayes_pls_golite062009
  • binding
    		•  4.16717332578111 bayes_pls_golite062009
  • mRNA binding
    		•  3.05425904007847 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.73925834998328 bayes_pls_golite062009
    		• 1.52879236550095 bayes_pls_golite062009
  • protein binding
    		•  1.32954276279597 bayes_pls_golite062009
  • transcription factor activity
    		•  0.873765500321315 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.852368751354665 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.632534695085793 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.56829350502235 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.294937517750882 bayes_pls_golite062009
    4
    Term Confidence Notes
  • nucleic acid binding
    		•  4.50398990564944 bayes_pls_golite062009
  • RNA binding
    		•  4.46119712758726 bayes_pls_golite062009
  • binding
    		•  4.16717332578111 bayes_pls_golite062009
  • mRNA binding
    		•  3.05425904007847 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.73925834998328 bayes_pls_golite062009
    		• 1.52879236550095 bayes_pls_golite062009
  • protein binding
    		•  1.32954276279597 bayes_pls_golite062009
  • transcription factor activity
    		•  0.873765500321315 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.852368751354665 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.632534695085793 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.56829350502235 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.294937517750882 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle