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Protein Overview: SPCC622.12c

General Information:
Name(s) found: SPCC622.12c [Sanger Pombe]
Description(s) found:
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  • pir||T41492 probable glutamate dehydrogenase (NADP) (EC 1.4.1.4) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|41016972|sp|P78804.2|DHE4_SCHPO RecName: Full=NADP-specific glutamate dehydrogenase; Short=NADP-GDH; AltName: Full=NADP-dependent glutamate dehydrogenase [NCBI NR]
  • gi|3821331|emb|CAA21868.1| NADP-specific glutamate dehydrogenase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075684|ref|NP_588184.1| NADP-specific glutamate dehydrogenase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • NADP-specific glutamate dehydrogenase [Sanger Pombe]
  • NADP-specific glutamate dehydrogenase OS=Schizosaccharomyces pombe GN=gdh1 PE=1 SV=2 [Swiss-Prot]
  • NADP-SPECIFIC GLUTAMATE DEHYDROGENASE: P78804; [pompepVF.fasta]
  • Probable NADP-specific glutamate dehydrogenase (EC 1.4.1.4) (NADP-GDH) [pompep4896]
  • |||NADP-specific glutamate dehydrogenase (putative) [pompepnew.fasta]
  • NADP-specific glutamate dehydrogenase (EC 1.4.1.4) (NADP-GDH) (NADP-dependent glutamate dehydrogenase) [4896.FASTAC]
  • |||NADP-specific glutamate dehydrogenase (predicted)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • nadp-specific glutamate dehydrogenase [Schizosaccharomyces pombe]gi|41016972|sp|P78804|DHE4_SCHPO NADP-specific glutamate dehydrogenase (NADP-GDH) (NADP-dependent glutamate dehydrogenase)gi|7492229|pir||T41492 probable glutamate dehydrogenase (NADP) (EC [nrdb_11152004_Chlamydomonas]
  • |||NADP-specific glutamate dehydrogenase |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • (P78804) Probable NADP-specific glutamate dehydrogenase (EC 1.4.1.4) (NADP-GDH) [pompep4896_normal_reversed]
  • NADP-specific glutamate dehydrogenase (NADP-GDH) (NADP-dependent glutamate dehydrogenase) [nr-271106-contam.fasta]
  • hypothetical protein SPCC622.12c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPCC622.12c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • |gdh1||NADP-specific glutamate dehydrogenase Gdh1 |Schizosaccharomyces pombe|chr 3|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • NADP-specific glutamate dehydrogenase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gdh1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 451 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    mitochondrion [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: glutamate biosynthetic process [ISSLink to PubMed article]
    ammonia assimilation cycle [ISS]
    Molecular Function: glutamate dehydrogenase (NADP+) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTPYEPEFQ QAYKEIVGSI ESSKLFEVHP ELKRVLPIIS IPERVLEFRV TWEDDKGNCR  60
   61 VNTGYRVQFN SALGPYKGGL RFHPSVNLSI LKFLGFEQIF KNALTGLPMG GGKGGSDFDP 120
  121 KGKSDNEIRR FSQAFMRQLF RYIGPQTDVP AGDIGVTGFV VMHMFGEYKR LRNEYSGVVT 180
  181 GKHMLTGGSN IRPEATGYGV VYYVKHMIEH RTKGAETLKG KRVAISGSGN VAQYAALKCI 240
  241 QEGAIVKSIS DSKGVLIAKT AEGLVPEEIH EIMALKEKRA SIADSASLCK KHHYIAGARP 300
  301 WTNVGEIDIA LPCATQNEVS GEEAAALIKQ GCRYVAEGSN MGSSAEAVEV FEKSRASGEG 360
  361 CWLAPGKAAN AGGVAVSGLE MAQNAQFSTW THAEVDAKLA GIMQNIFEQS TDVASKYCDS 420
  421 GSNNIPSLVD GANIAGFLKV ATAMQAVGDW W

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..451] PSI-BLAST 129.0 Glutamate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutamate dehydrogenase (NADP+) activity
    		•  4.50065200228697 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  4.08697502437308 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.54983447672782 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.66605122152932 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.43636049081724 bayes_pls_golite062009
  • catalytic activity
    		•  2.0643953589843 bayes_pls_golite062009
  • binding
    		•  1.77370305872094 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55390653047158 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.54527841865655 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.39067036188188 bayes_pls_golite062009
  • glutamate dehydrogenase [NAD(P)+] activity
    		•  0.994926158034199 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • structural molecule activity
    		•  0.345975336806588 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.0664389065992004 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle