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Protein Overview: brl1

General Information:
Name(s) found: brl1 / SPCC1919.15 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • ubiquitin-protein ligase E3 Brl1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 692 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    HULC complex [IDALink to PubMed articleLink to PubMed article]
    centromeric heterochromatin [IDALink to PubMed article]
    Biological Process: chromatin assembly [IMPLink to PubMed article]
    chromatin silencing [IMPLink to PubMed article]
    DNA replication-independent nucleosome assembly [TASLink to PubMed article]
    histone H2B ubiquitination [IDALink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    histone H3-K4 methylation [IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IEPLink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [IDALink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVVNESRKR RRLIHSEKET RRLDLGEEDD LELFQKEAAW RRSREYEHLT VLEKKLYEYW  60
   61 ESLVLKLDHY VAAALENHEQ SFEELEKITA SLYQPDDNLQ TLDLSLAEFS LIKDAQNYLN 120
  121 KYASYFQAHE PTLQKLAKFG SFKLKETPNV HEWIDQRQVH FTSMINYRTS QLKLALLKRK 180
  181 LSFFREALNS AELEWKRVQQ DQLTSASERS IENIADDIPA SEPKAILENG EGCLNDNDNI 240
  241 SKLKNNFQSQ ADLMQANINS KLDELSQKST RAAQLYVDIM GITDERVSRE PHYLELKGVL 300
  301 SSNEEKIESI NRDLSSLFED IQFFISQRTK RQKDIIDLKL ACVKEKQQLI KTLESSLTQI 360
  361 RNERDSLVAK QQMQYTNNLF FDDMMLLLSN LSNARVAILE GYSNRLCIWD RIERSKTGEM 420
  421 NNVLDEKEEI SASSALEKLI KNNSCLEAEL PSMYAAFDQS QSRLLKKYEE LETKEKKALE 480
  481 MHYEKARATQ KYFAAMKARD ILMTEKKTLK LAENKEHDYI GKLQEREHAL TKYESSLKAE 540
  541 LEVYKQIKEI YGKHSVEVLT EDKHLQVKQT KLTQKLEDLI ESVQKSGEKL MIMHQKLFHL 600
  601 QEEHTILSIK ASYNKKESHL INQAYETQEA QVYKGMLKCS VCNFSNWKSK LIPNCGHAFC 660
  661 SNCMEPFYEH KTSTCPQCET PFSVSDILTI HL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] MSA 1.461996 View MSA. No confident structure predictions are available.
    2 View Details [83..325] deduced N/A No confident structure predictions are available.
    3 View Details [326..620] PSI-BLAST 15.522879 Heavy meromyosin subfragment
    4 View Details [621..692] FFAS03 3.33 No description for 2f42A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle