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Protein Overview: lcf1

General Information:
Name(s) found: lcf1 / SPBC18H10.02 [Sanger Pombe]
Description(s) found:
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  • pir||T39766 probable long-chain-fatty-acid-CoA ligase (EC 6.2.1.3) SPBC18H10.02 [similarity] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582344|sp|O60135.1|LCF1_SCHPO RecName: Full=Long-chain-fatty-acid--CoA ligase 1; AltName: Full=Long-chain acyl-CoA synthetase 1; AltName: Full=Fatty acid activator 1 [NCBI NR]
  • gi|3006179|emb|CAA18399.1| long-chain-fatty-acid-CoA ligase Lcf1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112518|ref|NP_595726.1| long-chain-fatty-acid-CoA ligase Lcf1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • long-chain-fatty-acid-CoA ligase Lcf1 [Sanger Pombe]
  • Long-chain-fatty-acid--CoA ligase 1 OS=Schizosaccharomyces pombe GN=lcf1 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE LONG-CHAIN-FATTY-ACID--COA LIGASE: O60135; [pompepVF.fasta]
  • Putative long-chain-fatty-acid--CoA ligase [pompep4896]
  • |||putative long chain fatty acid coA ligase [pompepnew.fasta]
  • Lcf1 protein (Spbc18h10.02 protein) (EC 6.2.1.3) [4896.FASTAC]
  • |lcf1||long-chain-fatty-acid-CoA ligase activity (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative long-chain-fatty-acid--coa ligase [Schizosaccharomyces pombe]gi|3006179|emb|CAA18399.1| SPBC18H10.02 [Schizosaccharomyces pombe]gi|7492692|pir||T39766 probable long-chain-fatty-acid-CoA ligase (EC 6.2.1.3) SPBC18H10.02 [similarity] - fission ye [nrdb_11152004_Chlamydomonas]
  • |lcf1||long-chain-fatty-acid-CoA ligase activity |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O60135) Putative long-chain-fatty-acid--CoA ligase [pompep4896_normal_reversed]
  • |lcf1||long-chain-fatty-acid-CoA ligase Lcf1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC18H10.02 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Long-chain-fatty-acid--CoA ligase 1 (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) [nr-271106-contam.fasta]
  • SPBC18H10.02 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Long-chain-fatty-acid--CoA ligase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lcf1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 676 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: maintenance of stationary phase in response to starvation [IMPLink to PubMed article]
    long-chain fatty acid metabolic process [IGILink to PubMed article]
    chronological cell aging [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    ATP binding [IEA]
    long-chain fatty acid-CoA ligase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVQSKAISK PKEHESAIYR NANFPDHLVE TYSDDVHTLF DVFRHSVKQF GNKKAMGYRN  60
   61 LVKEHVETKM VTKVVDGEKK EVPKSWSYFE LSDYNYLSFN DIYDKALRYA GALRKLGLNK 120
  121 GDKFELYAPT SAFWLLTAEA CLSQSMTIVT AYDTLGEEGL LHSLRESGVR GMYTEGHLLK 180
  181 TLVNPLKEIE SLEVIIYRND AKEEDIKTIQ EIRPNLKLIK FADFEKMSPP VEPDPPSPEE 240
  241 ICCIMYTSGS TGLPKGVILS HKNMVAIVTA IVKHVPEVTS KDYLLAYLPL AHILEFAFEN 300
  301 ICLAWGGTIG YANVRTLVDT NCRNCKGDIN TFRPTIMVGV PAVWEMVRKG IMSKLNAASA 360
  361 VKRSVFWTAY YTKAKLMRHN LPGSCVLDTA VFNKIRSMGT GGRLRYTLSG GSALSPDTKR 420
  421 FLSIVLCPML IGYGLTEISA AAMVQNPACF NLDDSAGSLL PCTEMKLVDC EEGNYNSHGH 480
  481 PPRGEIWLRG PSLTRGYLNR DKENKESFTP DGWFRTGDVG ELTPEGLLRI IDRKKNLVKT 540
  541 QNGEYIALEK LESRYRTSSL VSNICVYADQ TKVKPLAIIV PNEPVVRKLA TEQAGLSPDA 600
  601 SWEEVCHNKK VRQLVYDDLI RIGRSHHFAN IELIQNVVLV PIEFTPENGL VTAAQKLQRR 660
  661 KILDRFKKEI DAAYAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..676] PSI-BLAST 126.0 No description for 2p2bA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle