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Protein Overview: clr1

General Information:
Name(s) found: clr1 / SPBC2D10.17 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • cryptic loci regulator Clr1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1238 amino acids

    Gene Ontology:
    Cellular Component: mating-type region heterochromatin [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    telomeric heterochromatin [IDALink to PubMed article]
    NuRD complex [IDALink to PubMed article]
    rDNA heterochromatin [IDALink to PubMed article]
    centromeric heterochromatin [IDALink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    chromatin modification [IEA]
    chromatin silencing at centromere [IMPLink to PubMed article]
    chromatin silencing at rDNA [IMPLink to PubMed article]
    chromatin silencing [IMPLink to PubMed article]
    chromatin silencing at silent mating-type cassette [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPDISSSE TLTELQQLRL LYFFCFYHAA PFNVKTLVHS LIPPGALSYL LSTYDILRPW  60
   61 LMALRVREGP VNDISTIVQL YEEIVKTGFF INPPPFESYS QTLVARITTL GRPKLQVQQE 120
  121 AQSEVYQRAS TNTQQQVSNV SHGNFKPNSS VNTEPNTSIL SNSKYAGIKP FDFQSSSQNP 180
  181 GLVCEQKTFY QHQFRPFSNL PSNKSSPVKH VSPNVKNNSK KTASSVNSNH SSIPSSITKS 240
  241 NISSLDVYGS EKLISSGSQQ PGHGMVQTTS DKVNASASLY DRSPSKKDIT SSRNTSSYNL 300
  301 GSMRNPSTLK NAAHANPFEG LRFQGSSAVL KEGLNSTVKK TFFDNLNSEK VCPSVSPFLT 360
  361 PDNIASSILY STASFSRSKP DRPRLNLSLE LKLMQNELNK GQLKKQFKGD LRNLADWNNL 420
  421 SLVSSKFPSL PITNLRPDGS FLKHRRFNEE IAYNRQTLEK AIKQLDLSPD KVIQLREQNG 480
  481 VAVNGRVCYP TRNKHSEISA QSSSSLGVTK SLASEVYSSS TVDTISKLNT DKDNYLIKSK 540
  541 KEPIQQKSVS SETTLVKPSS TSSYIDTTNN VLKTNSSFKS SGLTSGPRNE KELLPEGIPT 600
  601 SHNNSETQAQ TADVSNIAAS ADGIYNSDQE KPPEKLDVTK RAFGREIENS NEKELLTSTF 660
  661 LSPSAESQVC LAEIKTIRPG LVPKKQFSVD QNNVISDNTD CSLPKPSNSK LSSISSDGDA 720
  721 SSNRMAVPDK SPFVHAAPNS KALTKDSFST HISVSSLLHS DNEISPIDST RKDYFTSKDS 780
  781 NLQTLKEDAS STKQAKDSGT NDFDKLISGN DVSKNNSGEE QSRSALKPLI SGKLSSCESI 840
  841 NLTKDISTVK RKEYFGIEST SSKQPFHDTG SIKIPAKRSF DTIDKDFRSS NIPFADKIKE 900
  901 DGGDKNVISS IHITTELPKS MPVEVPTNAG AQSDQSNVVD SESLNLRENI STSVADVSLS 960
  961 QAGNEAVLSK KACKPLVLID PFEEKVLKAF NMLSKGYAEY RCQWEGCLAN LHSLENFIKH1020
 1021 VLLLHHPKSC SVVKCLWASC DMVLPSEEFE MHLRGHLNNI RLNCEVSNCK KCFSNYEDMF1080
 1081 KHLQHSHLPF KFTPESFIKI RNGNVKEEAR RTRNAYTQKS GEVECFMETC TPIAKPAPAN1140
 1141 WYPVPPPGFN SSLLSRLTQS NQSKDKIIAA LAKRNVYKSF AGLYDSKGKN DNTGYDFDSN1200
 1201 YARVGRHGSF ILPVSKSVPT PSLLIEGSIV QRKNIKIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..111] deduced N/A No confident structure predictions are available.
    2 View Details [112..192] deduced N/A No confident structure predictions are available.
    3 View Details [193..293] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [294..352] deduced N/A No confident structure predictions are available.
    5 View Details [353..595] deduced N/A No confident structure predictions are available.
    6 View Details [596..701] FFAS03 1.08 Solution structure of the Kruppel-associated box (KRAB) domain
    7 View Details [702..933] deduced N/A No confident structure predictions are available.
    8 View Details [934..1238] FFAS03 1.46 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • nucleic acid binding
    		•  2.35084112049258 bayes_pls_golite062009
  • DNA binding
    		•  2.22582111349682 bayes_pls_golite062009
  • binding
    		•  2.0499154380126 bayes_pls_golite062009
  • protein binding
    		•  0.477323490762673 bayes_pls_golite062009
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle