Protein Overview: SPAC31G5.15

General Information:
Name(s) found:	SPAC31G5.15 [Sanger Pombe]
Description(s) found: Found 18 descriptions. SHOW ALL	phosphatidylserine decarboxylase [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	980 amino acids
Gene Ontology:
Cellular Component:	cell division site [IDA] fungal-type vacuole membrane [ISS] cytosol [IDA] Golgi membrane [ISS]
Biological Process:	phosphatidylethanolamine biosynthetic process [IGI] regulation of cell morphogenesis [IGI] regulation of cytokinesis [IGI] phosphatidylcholine biosynthetic process [ISS]
Molecular Function:	phosphatidylserine decarboxylase activity [IGI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFTKSCRSA NTLRKGIKNG KLILKIIVND VCCWVLIKVT NKQIDNVESC LSGDESNDSK  60
   61 KSSASFYMKL KYGSYRALAD NILSTDENRK EDIAVFDVPL PNGLQIDTFT LCLYRKSKWK 120
  121 KQIVGEAYIG IQALLLSTNP DETCKYPVIS PPSGRNKENQ SPSHQICNLS LKWIIYDPED 180
  181 ADADSKTLAK AWLQQIKMNQ TSIDPMSNIS KSLKELEVDN VESDLEDSSF IAEPDSSIPP 240
  241 SESSVSISTD TGKETPPSKS KKSSNQPYVS IGEGNSDLLG FVFLEIISVS NLPPLKNVFR 300
  301 TGFDMDPFVI TAFSKNIFRT KWLRHNLNPV YNEKFLFEVG AFESNYDLVF KVVDHDKMSL 360
  361 NDSIAVGSFN VQSIINSSAQ VDPETGLYSF NIETSSPSQD TSSKAEDSPT VQKIADDFSS 420
  421 AVGKDLRTDI IEQIIPLTLC CKHDFSTPRD VKLSFKAMFF PIAALRQKFW RVMLAQYGDI 480
  481 EDGHIGKLGM YAVLDTLGSN IPNSMVDDIY TELSSKNHDD TSDSITVDEA VICLERLVDL 540
  541 VCHQDQQATQ TPQSPSSNEE SGPGTPTQTS DQYEDSEDSR NFPSKLYLVY LSNCPLCLKF 600
  601 KLSKVNQQKA TVHLATCASH DWKRVDRLMM TSYVSLNQAQ RRWFSKAFAK VVYGSSKVGS 660
  661 TSATTLVQNR QTGQIQEEKM NAYVRIGIRL LYRGIRNRRI EGSKVKKILR SLTLKQGMKY 720
  721 DSPISVKEIK PFIRFFDLNM NEVDMPVGGF KTFNEFFYRK LKPGSRPCAF PDNPDILVSP 780
  781 ADSRIVAYEC IEKATTYWIK GTEFTVERLL GYSNEAQRFV GGSICISRLA PQDYHRFHSP 840
  841 VNGCIGPITK IEGQYYTVNP MAIRSYLDVF GENVRVLIPI DSNEFGKVML VAVGAMMVGS 900
  901 TVLTVDEGKI VQRSDELGYF KFGGSTVITL FEPNVTSFDE DLLRNSKTKI ETLVKMGERI 960
  961 GQKIDPNKPT DAEDHSKSDS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ste13	No Comments	Unpublished Data

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..390]	PSI-BLAST	20.69897	Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)
2	View Details	[391..737]	PSI-BLAST	7.69897	Carboxyl-terminal src kinase (csk)
3	View Details	[738..810]	PSI-BLAST	48.69897	No description for 2i0eA was found.
4	View Details	[811..980]	MSA	5.265982	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
phosphoric diester hydrolase activity	3.96663444882989	bayes_pls_golite062009
phospholipase activity	3.3535603060637	bayes_pls_golite062009
phosphoric ester hydrolase activity	3.27299307330343	bayes_pls_golite062009
phospholipase C activity	3.23617371612061	bayes_pls_golite062009
glycerophosphodiester phosphodiesterase activity	3.0365240271671	bayes_pls_golite062009
inositol or phosphatidylinositol phosphodiesterase activity	2.723593331359	bayes_pls_golite062009
phosphoinositide phospholipase C activity	2.723593331359	bayes_pls_golite062009
lipase activity	1.30779031242608	bayes_pls_golite062009
catalytic activity	1.22328099675039	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.936568622355831	bayes_pls_golite062009
hydrolase activity	0.923065005246688	bayes_pls_golite062009
binding	0.105617039092967	bayes_pls_golite062009
phospholipid binding	0.0627743727162695	bayes_pls_golite062009

2

Term	Confidence	Notes
kinase activity	2.00477442267658	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.98118547704406	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.95139794143606	bayes_pls_golite062009
transferase activity	1.80001061545783	bayes_pls_golite062009
protein kinase activity	1.42061676948467	bayes_pls_golite062009
lipid kinase activity	1.3504796246251	bayes_pls_golite062009
protein serine/threonine kinase activity	1.24344027856943	bayes_pls_golite062009
catalytic activity	1.21655087018101	bayes_pls_golite062009
choline kinase activity	1.18757364210199	bayes_pls_golite062009
binding	1.16936304731867	bayes_pls_golite062009
phosphoinositide 3-kinase activity	1.10484220525143	bayes_pls_golite062009
1-phosphatidylinositol-3-kinase activity	1.04034573968654	bayes_pls_golite062009
inositol or phosphatidylinositol kinase activity	0.97254836668426	bayes_pls_golite062009
protein binding	0.287262599697657	bayes_pls_golite062009

3

No functions predicted.

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle