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Protein Overview: ucp8

General Information:
Name(s) found: ucp8 / SPBC83.01 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • UBA/EH/EF hand domain protein Ucp8 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 884 amino acids

    Gene Ontology:
    Cellular Component: actin cortical patch [ISSLink to PubMed article]
    Biological Process: endocytosis [ISSLink to PubMed article]
    intracellular protein transport [ICLink to PubMed article]
    actin cortical patch assembly [ISSLink to PubMed article]
    receptor-mediated endocytosis [NASLink to PubMed article]
    Molecular Function: ubiquitin binding [ISSLink to PubMed article]
    polyubiquitin binding [TASLink to PubMed article]
    calcium ion binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPLQLSPIE QQEFDRLLES LHPEQKDLIP GSVIGPFLLK FGLPQKILAK IWDYCDQEDK  60
   61 GSLDRNQVYA CFRLISQAQR GATLQELDYN KAGDPPILPK QAKDDHHIKR SSSETADFTP 120
  121 FRIPINPDER SEYEKEFREN LRGHEDSARP GCMPSSIAKP ILLKSSLHYA VLAQIWNLAD 180
  181 SAHVGYLEMY QYVIARHLVA ICKQYNLIHL PRSLPADVIE SAKSETPAMN TNIEQGVTQP 240
  241 SLVNTEQLSH QQSISSTKSS KLDEISADNN AQSAVDNKYS SPPQTIDPQA NIKALITPED 300
  301 RSNFYQLFSK IDNENKGYIV GGEAVPFFMA SHLDSEELAR IWDTVDTQDR GYIDKDEFAV 360
  361 AMEIIKLRLS GKSLASILAY DDNPTEPTMQ QNLVSDDTNA STAVPVAFTN DNVSNVPLSV 420
  421 ADNEPNSTLN LLASSDTAAF EPTAVSLHEN PSSSLEDLQS AFQNTSFQDQ VSTQNQANTA 480
  481 DISQNTESGS STQGQMFGIP PTTQSIPLKM AGFPGGVNSS LTDIKEEEAV SENAPQQEER 540
  541 SFEQIKTSIH IAPENISAIE ESKSVPLPTS FATTIPGSTS AALDDQQTTE APFEEPDEPA 600
  601 HEPTEEEQEE MRKLEEKIES TKYGLETIQT SGKTIKQRIE QKKTRLMILR EELQELDAIK 660
  661 EEAQKQISQS LIADQQLSTQ IGSVGMGKKQ AVKELRKLQA KIDSIIADSM SPMGTGAVNS 720
  721 PAIKPQVTPA PPTPAPTPAV KHHPPPPPVR SSISPSMPPA PLTHANSSTP MNYVSQPESP 780
  781 PQSYESIQND NELLQELLSM GFPREKAVIA LEATNYDVNE VSDSDSKLSC SKYMCSFTFI 840
  841 YSDFTSNITN NYRPRIYYLA QFSVCENQSI MTFRLQPFHV IYEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] PSI-BLAST 29.0 Pob1
    2 View Details [84..271] FFAS03 3.62 No description for 2qptA was found.
    3 View Details [272..749] PSI-BLAST 29.522879 Heavy meromyosin subfragment
    4 View Details [750..884] PSI-BLAST 6.69897 No description for 2i1jA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  3.96919556235483 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.49668552859347 bayes_pls_golite062009
  • structural constituent of muscle
    		•  3.12414907235012 bayes_pls_golite062009
  • microfilament motor activity
    		•  2.9702957313812 bayes_pls_golite062009
  • binding
    		•  2.59835122922082 bayes_pls_golite062009
  • motor activity
    		•  2.57627414053278 bayes_pls_golite062009
  • actin filament binding
    		•  2.35534489389161 bayes_pls_golite062009
  • myosin binding
    		•  2.34125070430971 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.06646671333275 bayes_pls_golite062009
  • calcium ion binding
    		•  1.75413488311654 bayes_pls_golite062009
  • protein binding
    		•  1.36984860219682 bayes_pls_golite062009
  • metal ion binding
    		•  1.19984728454368 bayes_pls_golite062009
  • cation binding
    		•  1.19984728454368 bayes_pls_golite062009
  • ion binding
    		•  1.1923653453763 bayes_pls_golite062009
  • actin monomer binding
    		•  0.9954841049256 bayes_pls_golite062009
  • tubulin binding
    		•  0.710693016758742 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.61866037435065 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.401233649632102 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.341013054040087 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.32485782650283 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.324368071436317 bayes_pls_golite062009
  • microtubule binding
    		•  0.278596514315141 bayes_pls_golite062009
  • structural molecule activity
    		•  0.234626449126289 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.116648335890738 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle