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Protein Overview: SPBC29A3.13

General Information:
Name(s) found: SPBC29A3.13 [Sanger Pombe]
Description(s) found:
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  • pir||T40084 PWWP domain protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582204|sp|O59676.1|YB8D_SCHPO RecName: Full=PWWP domain-containing protein C29A3.13 [NCBI NR]
  • gi|3006149|emb|CAA18390.1| PWWP domain protein Pdp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112633|ref|NP_595841.1| PWWP domain protein [Schizosaccharomyces pombe] [NCBI NR]
  • PWWP domain protein [Sanger Pombe]
  • PWWP domain-containing protein C29A3.13 OS=Schizosaccharomyces pombe GN=SPBC29A3.13 PE=1 SV=1 [Swiss-Prot]
  • PWWP DOMAIN PROTEIN; PUTATIVE NUCLEAR PROTEIN; PUTATIVE CELL GROWTH: ;N0ACC; [pompepVF.fasta]
  • PWWP DOMAIN PROTEIN; PUTATIVE NUCLEAR PROTEIN; POSSIBLE CELL GROWTH: ;N0ACC; [pompepV13]
  • PWWP domain protein, putative nuclear protein, possible cell growth [pompep4896]
  • |||PWWP domain protein [pompepnew.fasta]
  • SPBC29A3.13 protein [4896.FASTAC]
  • |||PWWP domain protein|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • PWWP domain protein; putative nuclear protein; possible cell growth [Schizosaccharomyces pombe]gi|3006149|emb|CAA18390.1| SPBC29A3.13 [Schizosaccharomyces pombe]gi|7493242|pir||T40084 PWWP domain protein - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O59676) PWWP domain protein, putative nuclear protein, possible cell growth [pompep4896_normal_reversed]
  • |pdp1||PWWP domain protein Pdp1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC29A3.13 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC29A3.13 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 359 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    nuclear chromatin [ISSLink to PubMed article]
    Biological Process: DNA damage checkpoint [IGILink to PubMed article]
    chromatin remodeling [ISSLink to PubMed article]
    regulation of histone H4-K20 methylation [IGILink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    methylated histone residue binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNARTNAKR RRLSSKQGGL SISEGKESNI PSVVEESKDN LEQASADDRL NFGDRILVKA  60
   61 PGYPWWPALL LRRKETKDSL NTNSSFNVLY KVLFFPDFNF AWVKRNSVKP LLDSEIAKFL 120
  121 GSSKRKSKEL IEAYEASKTP PDLKEESSTD EEMDSLSAAE EKPNFLQKRK YHWETSLDES 180
  181 DAESISSGSL MSITSISEMY GPTVASTSRS STQLSDQRYP LSSNFDHRGE AKGKGKQPLK 240
  241 NPQERGRISP SSPLNDQTKA LMQRLLFFRH KLQKAFLSPD HLIVEEDFYN ASKYLNAISD 300
  301 IPFLNYELIT STKLAKVLKR IAFLEHLEND ELYDIRQKCK NLLYSWAMFL PNEPSIKGM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] PSI-BLAST 19.69897 DNA methyltransferase DNMT3B
    2 View Details [199..278] deduced N/A No confident structure predictions are available.
    3 View Details [279..359] FFAS03 1.23 Solution structure of the N-terminal Domain I of mouse transcription elongation factor S-II protein 3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone methyltransferase activity
    		•  4.99595771339053 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  4.19447715401381 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  4.17343835151493 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  4.17343835151493 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  4.17343835151493 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.99360930536438 bayes_pls_golite062009
  • DNA (cytosine-5-)-methyltransferase activity
    		•  3.47194555232584 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  3.07442486638326 bayes_pls_golite062009
  • binding
    		•  3.03932294945523 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.54859161354698 bayes_pls_golite062009
  • histone binding
    		•  2.53075587257882 bayes_pls_golite062009
  • unmethylated CpG binding
    		•  2.40629601442755 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  2.35081504375623 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.18489564426455 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K36 specific)
    		•  1.77912558508065 bayes_pls_golite062009
  • protein binding
    		•  1.76914488602752 bayes_pls_golite062009
  • DNA binding
    		•  1.74895470739534 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.72728430471046 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.45012620929102 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.37282797213354 bayes_pls_golite062009
  • histone methyltransferase activity (H4-K20 specific)
    		•  1.33068639111811 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.29059770639777 bayes_pls_golite062009
  • transcription factor binding
    		•  1.24998724455481 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.07648674416752 bayes_pls_golite062009
  • estrogen receptor binding
    		•  1.07290804941322 bayes_pls_golite062009
  • transcription factor activity
    		•  0.865067316865618 bayes_pls_golite062009
  • chromatin binding
    		•  0.50732149810757 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.0798851485729806 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle