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Protein Overview: syj1

General Information:
Name(s) found: syj1 / SPBC2G2.02 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1076 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: phosphatidylinositol metabolic process [ISSLink to PubMed article]
    inositol lipid-mediated signaling [ICLink to PubMed article]
    endocytosis [ISSLink to PubMed article]
    phosphoinositide dephosphorylation [ISSLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [ISSLink to PubMed article]
    inositol-polyphosphate 5-phosphatase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQCLLREKPR SLALVNKDHA LMFHSVPQNK NSLSVCVAEF TALSEKPLEG FRKISSHRIY  60
   61 GTLGLIELEG SNFLCVISGA SEVARVRDKE RVFRIMEVCF YSVNRSNWDH IRQENYSPDI 120
  121 PDGYDTDTQG YDSYKYAAEP FSSLRKLLTN GSFYFSLDFD ITTRLQLRTS QTMTEPQYDS 180
  181 MHTQFMWNEF MLRQLIKFRS HLNGDEKSAL DGCRFFTCAI RGFASTEQFK LGIQTIRLSL 240
  241 ISRLSSLRAG TRFLSRGVDD DGNVANFVET ETILDSSKYC VSYCQVRGSI PIFWEQEGVQ 300
  301 MFGQKIDITR SLEATRAAFE KHFTSLIEEY GPVHIINLLG TGSGERSLSE RLRQHIQLSP 360
  361 EKDLIHLTEF DYHSQIRSFE DANKIRPMIY SDAETFGFYF ENNEGQSIVV QDGVFRTNCL 420
  421 DCLDRTNVIQ NLVSRVFLEQ VMIYTRQNAG YDFWQVHSTI WANNGDALAR IYTGTGALKS 480
  481 SFTRKGKLSI AGALNDLSKS VGRMYINNFQ DKGRQETIDL LLGRLIDQHP VILYDPIHEY 540
  541 VNHELRKREN EFSEHKNVKI FVASYNLNGC SATTKLENWL FPENTPLADI YVVGFQEIVQ 600
  601 LTPQQVISAD PAKRREWESC VKRLLNGKCT SGPGYVQLRS GQLVGTALMI FCKESCLPSI 660
  661 KNVEGTVKKT GLGGVSGNKG AVAIRFDYED TGLCFITSHL AAGYTNYDER DHDYRTIASG 720
  721 LRFRRGRSIF NHDYVVWFGD FNYRISLTYE EVVPCIAQGK LSYLFEYDQL NKQMLTGKVF 780
  781 PFFSELPITF PPTYKFDIGT DIYDTSDKHR VPAWTDRILY RGELVPHSYQ SVPLYYSDHR 840
  841 PIYATYEANI VKVDREKKKI LFEELYNQRK QEVRDASQTS YTLIDIAGSV AGKPNLIPHL 900
  901 PANGVDKIKQ PSSERSKWWF DDGLPAKSIA APPGPEYRLN PSRPINPFEP TAEPDWISNT 960
  961 KQSFDKKSSL IDSIPALSPA PSSLARSSVS SQRSSTSIIP IKPNKPTKPD HLVAPRVKPL1020
 1021 LPPRSGSSSS GVPAPNLTPV NVPPTPPPRK SSASQRSGDL LASSPEESSI SWKPLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] deduced N/A No confident structure predictions are available.
    2 View Details [136..377] MSA 1.177947 View MSA. No confident structure predictions are available.
    3 View Details [378..529] MSA 1.191974 View MSA. Confident ab initio structure predictions are available.
    4 View Details [530..885] PSI-BLAST 112.0 Synaptojanin, IPP5C domain
    5 View Details [886..1076] FFAS03 1.11 No description for 2j63A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • hydrolase activity, acting on ester bonds
    		•  6.16986356176974 bayes_pls_golite062009
  • phosphatase activity
    		•  5.90350467872925 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  5.84927924311254 bayes_pls_golite062009
  • phosphatidylinositol bisphosphate phosphatase activity
    		•  5.76202422677892 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
    		•  5.57319461575586 bayes_pls_golite062009
  • phosphoinositide 5-phosphatase activity
    		•  5.57319461575586 bayes_pls_golite062009
  • inositol-polyphosphate 5-phosphatase activity
    		•  4.20215185632047 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  3.88924621938812 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  3.07322777760243 bayes_pls_golite062009
  • phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
    		•  2.64934277728302 bayes_pls_golite062009
  • phosphatidylinositol-4-phosphate phosphatase activity
    		•  2.64934277728302 bayes_pls_golite062009
  • inositol trisphosphate phosphatase activity
    		•  2.32855198081691 bayes_pls_golite062009
  • phosphatidylinositol-3-phosphatase activity
    		•  1.98439062808392 bayes_pls_golite062009
  • hydrolase activity
    		•  1.94088348434922 bayes_pls_golite062009
  • catalytic activity
    		•  1.76511376991978 bayes_pls_golite062009
  • phosphatidylinositol trisphosphate phosphatase activity
    		•  1.43486520454637 bayes_pls_golite062009
  • binding
    		•  1.10604548818653 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.10196417513158 bayes_pls_golite062009
  • DNA binding
    		•  1.08923919229723 bayes_pls_golite062009
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
    		•  0.938520838175434 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.934018277503377 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.620825895803427 bayes_pls_golite062009
  • nuclease activity
    		•  0.531982382500929 bayes_pls_golite062009
  • protein binding
    		•  0.476649214025345 bayes_pls_golite062009
  • exonuclease activity
    		•  0.219613338022829 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.213742479001316 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  0.137101173922861 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle