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Protein Overview: dus3

General Information:
Name(s) found: dus3 / SPAC16.04 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • tRNA dihydrouridine synthase Dus3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 617 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    Biological Process: tRNA modification [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    tRNA dihydrouridine synthase activity [ISSLink to PubMed article]
    FAD binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELETGAVP IREEFLVKQD GNKKRKRKER GQNKRREKIH VKENNALCPA ISIGNECPYK  60
   61 ENCKFPHDVE AYLATKAPDI GDKCPIFERY GVCPAGFKCR WLAGHVVINA DGKYELIKKP 120
  121 DGQFTLFTVN TVGKEVQRKL RTKQLDLSKA ESIISAVLGE EKPDPSSKVS NIPEENRDAT 180
  181 SAISEGKETE SVSLEETGVL KNQTVSVNVD LKEISSQARS NIALPTLRPQ EKNLIDWRDR 240
  241 KILAPLTTVG NPPFRRLCGS LGADTFYSEM AMCYPLMQGH QPEWALVRGL NYEREMMRGG 300
  301 RRGILGVQLA TGKLWQATKT AQVIAEQCDG VDFLDLNCGC PIDLVFRQGA GSSLLENPGR 360
  361 LLRNLQGMDA VSGQIPVTVK LRMGNKDDHP VVKNLIGRIF NETNTSAATL HGRSRQQRYS 420
  421 KNANWDYIGE IASKVKSMNE RIDELPEDSL RTQPLSLIGN GDCYSWQDWY DGVNKGVDTV 480
  481 MIARGALVKP WIFEEIEARQ FIDKSSTQRL EMLEQYCNNG LEYWGSDSQG VNTTRRFFLE 540
  541 FMSFFHRYTP IALYEVQRPR LNDRPPLYTA RDEMETLLAS NKVTDWVKLS EFFLGPTPER 600
  601 FTFTPKHKSN SVEEAEG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] PSI-BLAST 16.522879 Structural Basis for Recognition of the mRNA Class II AU-Rich Element by the Tandem Zinc Finger Domain of TIS11d
    2 View Details [113..223] deduced N/A No confident structure predictions are available.
    3 View Details [224..617] PSI-BLAST 38.39794 Crystal structure of a putative flavin oxidoreductase with flavin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleic acid binding
    		•  2.13899087582327 bayes_pls_golite062009
  • catalytic activity
    		•  1.94749091175302 bayes_pls_golite062009
  • tRNA dihydrouridine synthase activity
    		•  1.94490879164338 bayes_pls_golite062009
  • binding
    		•  1.2785695107981 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.876786102965635 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.80115790656025 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle