YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: dus3
Organism: Schizosaccharomyces pombe
Length: 617 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dus3.

Description E-value Query
Range
Subject
Range
DUS3L_XENLA - tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Xenopus laevis GN=dus3l PE=2 SV=1
407.0 [0..3] [612..83]
gi|14602971, gi|... - gi|24308187|ref|NP_064560.1| dihydrouridine synthase 3-like [Homo sapiens], gi|14602971|gb|AAH09973....
gi|190690551, gi... - gi|190691915|gb|ACE87732.1| dihydrouridine synthase 3-like (S. cerevisiae) protein [synthetic constr...
401.0 [0..3] [612..76]
gi|89272495 - gi|89272495|emb|CAJ83250.1| dihydrouridine synthase 3-like protein [Xenopus tropicalis]
400.0 [0..3] [612..82]
gi|148706257, gi... - gi|74186083|dbj|BAE34157.1| unnamed protein product [Mus musculus], gi|255003775|ref|NP_659107.2| di...
391.0 [0..3] [612..67]
DUS3L_RAT - tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Rattus norvegicus GN=Dus3l PE=2 SV=1
390.0 [0..3] [612..70]

Back

Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELETGAVP IREEFLVKQD GNKKRKRKER GQNKRREKIH VKENNALCPA ISIGNECPYK  60
   61 ENCKFPHDVE AYLATKAPDI GDKCPIFERY GVCPAGFKCR WLAGHVVINA DG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1rgoA
Description: Structural Basis for Recognition of the mRNA Class II AU-Rich Element by the Tandem Zinc Finger Domain of TIS11d
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [113-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYELIKKPDG QFTLFTVNTV GKEVQRKLRT KQLDLSKAES IISAVLGEEK PDPSSKVSNI  60
   61 PEENRDATSA ISEGKETESV SLEETGVLKN QTVSVNVDLK EISSQARSNI A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [224-617]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPTLRPQEKN LIDWRDRKIL APLTTVGNPP FRRLCGSLGA DTFYSEMAMC YPLMQGHQPE  60
   61 WALVRGLNYE REMMRGGRRG ILGVQLATGK LWQATKTAQV IAEQCDGVDF LDLNCGCPID 120
  121 LVFRQGAGSS LLENPGRLLR NLQGMDAVSG QIPVTVKLRM GNKDDHPVVK NLIGRIFNET 180
  181 NTSAATLHGR SRQQRYSKNA NWDYIGEIAS KVKSMNERID ELPEDSLRTQ PLSLIGNGDC 240
  241 YSWQDWYDGV NKGVDTVMIA RGALVKPWIF EEIEARQFID KSSTQRLEML EQYCNNGLEY 300
  301 WGSDSQGVNT TRRFFLEFMS FFHRYTPIAL YEVQRPRLND RPPLYTARDE METLLASNKV 360
  361 TDWVKLSEFF LGPTPERFTF TPKHKSNSVE EAEG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.39794
Match: 1vhnA
Description: Crystal structure of a putative flavin oxidoreductase with flavin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.13899087582327 bayes_pls_golite062009
catalytic activity 1.94749091175302 bayes_pls_golite062009
tRNA dihydrouridine synthase activity 1.94490879164338 bayes_pls_golite062009
binding 1.2785695107981 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.876786102965635 bayes_pls_golite062009
oxidoreductase activity 0.80115790656025 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle