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Protein Overview: SPAC2C4.07c

General Information:
Name(s) found: SPAC2C4.07c [Sanger Pombe]
Description(s) found:
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  • pir||T38518 ribonuclease II RNB family protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74581952|sp|O14040.1|DIS3L_SCHPO RecName: Full=Dis3-like exonuclease C2C4.07c [NCBI NR]
  • gi|2414618|emb|CAB16367.1| ribonuclease II (RNB) family [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115422|ref|NP_594510.1| ribonuclease II (RNB) family [Schizosaccharomyces pombe] [NCBI NR]
  • ribonuclease II (RNB) family [Sanger Pombe]
  • Exosome complex exonuclease RRP44 OS=Schizosaccharomyces pombe GN=rrp44 PE=2 SV=1 [Swiss-Prot]
  • Dis3-like exonuclease C2C4.07c OS=Schizosaccharomyces pombe GN=SPAC2C4.07c PE=2 SV=1 [Swiss-Prot]
  • RIBONUCLEASE II RNB FAMILY PROTEIN; DIS3-LIKE; SUBCELLULAR LOCALIZATION OF GFP FUSION- CYTOPLASM: O14040;Q9USE3; [pompepVF.fasta]
  • Ribonuclease II RNB family protein, dis3-like [pompep4896]
  • |||ribonuclease II RNB family protein [pompepnew.fasta]
  • SPAC2C4.07c protein [4896.FASTAC]
  • |||ribonuclease II (RNB) family|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • ribonuclease II RNB family protein; dis3-like [Schizosaccharomyces pombe]gi|2414618|emb|CAB16367.1| SPAC2C4.07c [Schizosaccharomyces pombe]gi|7493295|pir||T38518 ribonuclease II RNB family protein - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||ribonuclease II |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O14040) Ribonuclease II RNB family protein, dis3-like [pompep4896_normal_reversed]
  • SPAC2C4.07c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC2C4.07c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 927 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cellular response to stress [IEPLink to PubMed article]
    RNA catabolic process [ISSLink to PubMed article]
    Molecular Function: RNA binding [ISSLink to PubMed article]
    ribonuclease activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLKPNIRRK EKRNLLKGEA ALEKKGSIDR KTKNKAYPST THDPHQNDDS NIPGLGSGLL  60
   61 ERIKDIVQRP TDTQLKGQDS NHKKASLTET KTEKAKVKPK AKKKNSKEKI SKSSKQDEHK 120
  121 TDVHKESVSK LSKNLESRNN RDENSAKREK NNSHQVEADT NNATEMVSSN AKKSVYPLYY 180
  181 DSATVKKGLK SGTLFKGTLR ILENHRSAFA CMEDIPDFYV DGPIARNRAF HNDVVIVEPV 240
  241 MNNDSPTEKS NFLQNGVEKV KIKDHDDELG GAMEHLERLE IKSVASFKGD SRTRARVVAI 300
  301 EKRAEISKIV GILRAPGWSL KNVEYVSKKS SYAIFIPKDK RLPFITIHKN DLSDLSGENW 360
  361 IENILKHHDQ LFSVEITRWS IYSRYPMGVL GEKLGNITDV EAYTNALLLE NGISSSPFSD 420
  421 EVLNCLPPDD WIISHEEIKK RRDLRNELII TIDPETARDL DDAVSCRALD NGTYEVGVHI 480
  481 ADVTHFVKPD SALDKEAASR ATTVYLVQKA IPMLPPLLCE RLCSLNPNVE RLAFSVFWKL 540
  541 DSNGKEIGKR WFGKTVIKTC ARLAYSEAQG VIEGKSWDDA VGKPIGGTHT PKDVETSILT 600
  601 LCEISRKLRK DRFAKGAVEI NSTELKFQLD EYGMPNKCEV YEQTDANHLI EEFMLLANRS 660
  661 VAEHISKNFS NNSLLRRHAS PKEKQINEFC HFLKSMNFDF DASSSAAFNA SMVRLRSTFN 720
  721 EELVELFENM AVRSLNRAEY FCTGDFGEKT DWHHYALSFN HYTHFTSPIR RYPDIIVHRL 780
  781 LERSLKNTSP GIDKKNCSLV AAHCNEKKEK STTVQEDSQQ LFLSVYIAEY CKKHDKKSMP 840
  841 VQAFATRISG NSIDVYISEY GISNRVDLSS DDRIKSFIVA PDDSSVKITL FDDSQKTIAL 900
  901 TDRFQVYLYS DYSRTFFSIR CSLVSLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..214] MSA 2.244972 View MSA. No confident structure predictions are available.
    2 View Details [215..927] PSI-BLAST 135.0 No description for 2ix0A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ribonuclease activity
    		•  2.62839959678464 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51640430970576 bayes_pls_golite062009
  • DNA binding
    		•  1.75130537402007 bayes_pls_golite062009
  • binding
    		•  1.60192408330567 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.04185075327062 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.0113847021033 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.477952624136452 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.440010017405756 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.373494794810156 bayes_pls_golite062009
  • hydrolase activity
    		•  0.357828165699872 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.223941674251642 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.19668406318255 bayes_pls_golite062009
  • structural molecule activity
    		•  0.0731323814416581 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle