Protein Overview: SPBP8B7.17c

General Information:
Name(s) found:	SPBP8B7.17c [Sanger Pombe]
Description(s) found: Found 18 descriptions. SHOW ALL	phosphomethylpyrimidine kinase [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	506 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] cytosol [IDA]
Biological Process:	phosphorylation [IC] thiamin biosynthetic process [IEA]
Molecular Function:	ATP binding [IEA] phosphomethylpyrimidine kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISTCITVAG SDCSGGAGVQ ADLKVFTAHS VYGMSAVTAI TSQNTIGVNG VHLIPASYVE  60
   61 QQISACLLDV HCEVMKTGML FNQQILKVIV ESIDRFKIKK VVVDPLIATR KGALLVMPDY 120
  121 LELFVKELIP RAEVLIPNIA EALIILKHMT NEFVEIHHLE DVKAVGKKLI KAGCKNVVIR 180
  181 CDDIPFASDF FCSRETNMPP TWYLYVLCTS EGEVLLPQKW LASKTARGTS CALSSAVASN 240
  241 LAIGLDLVTA TQNAVSYTQR ALEMSFHLGR GANSLDYASA LTRLPYEKGE FINFVRYHPS 300
  301 ITPKWLSIVN HPFVEQLKAG TLSRLPFQKY LVLKYHMLIN NAQAAGMMAF SSSSISAIEH 360
  361 SAKIIQAIKE ENVTHLRICE QYGLSASQIT KSKPEIVKSH SLFIHDTAQQ DGLRGIQIAM 420
  421 LPFVFMIQEV VSQISASDGY PYVAWVEHCK DKSATSHIET LLESLETNSQ IISLSKVQHL 480
  481 LGILEKSLDF ERLVLDTSSS NESSVF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..283]	PSI-BLAST	57.154902	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)
2	View Details	[284..506]	PSI-BLAST	54.0	Structure of TenA from Bacillus subtilis

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
phosphomethylpyrimidine kinase activity	3.972577109569	bayes_pls_golite062009
carbohydrate kinase activity	2.34445983129813	bayes_pls_golite062009
thiaminase activity	2.33383885490808	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	2.29466565429735	bayes_pls_golite062009
kinase activity	2.28531824242987	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.27980720248925	bayes_pls_golite062009
transferase activity	2.15883296431019	bayes_pls_golite062009
catalytic activity	1.74474587246986	bayes_pls_golite062009
hydroxyethylthiazole kinase activity	1.28568044601242	bayes_pls_golite062009
thiamin-phosphate diphosphorylase activity	1.27602595951972	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.673555832721854	bayes_pls_golite062009
phosphofructokinase activity	0.37205329607884	bayes_pls_golite062009
nucleic acid binding	0.35385659578167	bayes_pls_golite062009
binding	0.2717506679077	bayes_pls_golite062009
transcription regulator activity	0.219913271321955	bayes_pls_golite062009
pyridoxal kinase activity	0.217863391052366	bayes_pls_golite062009
DNA binding	0.101423482181266	bayes_pls_golite062009

2

Term	Confidence	Notes
binding	0.653486090379666	bayes_pls_golite062009
catalytic activity	0.476060647762462	bayes_pls_golite062009
transcription regulator activity	0.37460460006397	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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