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Protein Overview: alg2

General Information:
Name(s) found: alg2 / SPBC11B10.01 [Sanger Pombe]
Description(s) found:
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  • gi|63054730|ref|NP_595621.2| mannosyltransferase complex subunit Alg2 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|46395952|sp|Q96WW6.1|ALG2_SCHPO RecName: Full=Alpha-1,3-mannosyltransferase alg2; AltName: Full=GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 2 [NCBI NR]
  • ref|NP_595620.1| glycosyltransferase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|157310409|emb|CAC37504.2| mannosyltransferase complex subunit Alg2 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|13872534|emb|CAC37505.1| SPBC11B10.01 [Schizosaccharomyces pombe] [NCBI NR]
  • mannosyltransferase complex subunit Alg2 [Sanger Pombe]
  • Alpha-1,3-mannosyltransferase alg2 OS=Schizosaccharomyces pombe GN=alg2 PE=2 SV=1 [Swiss-Prot]
  • GLYCOSYL TRANSFERASE: O13604;Q96WV8;Q96WW6; [pompepVF.fasta]
  • GLYCOSYLTRANSFERASE: CAC37504;CAC37505;O13604; [pompepV13]
  • Glycosyltransferase [pompep4896]
  • |c11B10.01|SPBC32H8.14|putative glycosyl transferase [pompepnew.fasta]
  • Putative alpha-1,3-mannosyltransferase ALG2 (EC 2.4.1.-) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) [4896.FASTAC]
  • ||SPBC32H8.14|glycosyl transferase family 1|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • glycosyltransferase [Schizosaccharomyces pombe]gi|13872534|emb|CAC37505.1| SPBC11B10.01 [Schizosaccharomyces pombe]gi|46395952|sp|Q96WW6|ALG2_SCHPO Putative alpha-1,3-mannosyltransferase ALG2 (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) [nrdb_11152004_Chlamydomonas]
  • (Q96WW6) Glycosyltransferase [pompep4896_normal_reversed]
  • |alg2|SPBC32H8.14|mannosyltransferase complex subunit Alg2 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC11B10.01 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • alpha-1,3-mannosyltransferase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Alpha-1,3-mannosyltransferase alg2 (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (Asparagine-linked glycosylation protein 2) [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    endoplasmic reticulum [ISSLink to PubMed article]
    Biological Process: oligosaccharide-lipid intermediate assembly [ISSLink to PubMed article]
    macromolecule glycosylation [ICLink to PubMed article]
    Molecular Function: glycolipid 6-alpha-mannosyltransferase activity [ISS]
    glycolipid mannosyltransferase activity [ISSLink to PubMed article]
    glycolipid 3-alpha-mannosyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQENSVHRS STKKTPIKIA FIHPDLGIGG AERLVVDAAV GLQSLGKEVV VFTSHCDKKH  60
   61 CFEEIRDGTI KVKVYGDWLP SSIFGRLSIF CSSLRQVYLT MILLTNYMHF DAIIVDQLST 120
  121 CVPFLLLASQ MILFYCHFPD KYLAKRGGIL KKLYRIPFDT VEAESVRLAD RIVVNSKFTA 180
  181 SVFKKAFPKI RKPLRIVHPC VDIEAASKPL EFQLPEKILY LRYSQRKLLI SVNRFERKKD 240
  241 IRLAIDAFSA LRDLSANRFP EYLLLVAGGY DIRVSENRRY LKELQEFCEQ KDLSYTTVKD 300
  301 NWDNITVAPS TNVLFLLSVP SKVRDALISS SRILLYTPEN EHFGIVPLEA MLRKVPVLAQ 360
  361 TNGGPLETVI DGKNGWLRPR DAKIWGNVIY EATTSTTYDT AAMGEAGSEW VKNEFSTDAM 420
  421 ARKFESEIMS GIRSITPEKR LMRRVNGLLA VFVLFMLFWG TCIIAATVPF AIIKLYFAQT 480
  481 YSSVKLGFML GTCIVSVSFL TFTVYAKLTN L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..511] PSI-BLAST 49.522879 Structure of glycogen synthase from Pyrococcus abyssi

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • alpha-1,3-mannosyltransferase activity
    		•  6.58172475060696 bayes_pls_golite062009
  • glycolipid mannosyltransferase activity
    		•  5.39233021873725 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  3.70184884300914 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  3.21859657603001 bayes_pls_golite062009
  • glycolipid 6-alpha-mannosyltransferase activity
    		•  2.81514353203234 bayes_pls_golite062009
  • glycolipid 3-alpha-mannosyltransferase activity
    		•  2.81514353203234 bayes_pls_golite062009
  • alpha-1,6-mannosyltransferase activity
    		•  2.81514353203234 bayes_pls_golite062009
  • catalytic activity
    		•  2.65148466065976 bayes_pls_golite062009
  • transferase activity
    		•  2.6268567881241 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.62403914335522 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  2.13085705769565 bayes_pls_golite062009
  • glycogen phosphorylase activity
    		•  1.55216954018473 bayes_pls_golite062009
  • glucosyltransferase activity
    		•  1.5162351691061 bayes_pls_golite062009
  • binding
    		•  1.22341386111754 bayes_pls_golite062009
  • UDP-glucosyltransferase activity
    		•  1.21599854394093 bayes_pls_golite062009
  • phosphorylase activity
    		•  1.16838250569299 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.354187614795831 bayes_pls_golite062009
  • alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
    		•  0.333194028937286 bayes_pls_golite062009
  • protein binding
    		•  0.0755094482594821 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  4.32270241054966E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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