YRC Public Data Repository - Protein Structure Prediction

Protein:	alg2
Organism:	Schizosaccharomyces pombe
Length:	511 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for alg2.

Description	E-value	Query Range	Subject Range
alg2 - mannosyltransferase complex subunit Alg2 ALG2_SCHPO - Alpha-1,3/1,6-mannosyltransferase alg2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=alg...	348.0	[0..1]	[511..1]
Y1607_METJA, YG0... - (Q59002) Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-), Uncharacterized glycosyltransferase ... Y1607_METJA - Uncharacterized glycosyltransferase MJ1607 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM...	251.0	[0..17]	[433..1]
gi\|16605561, gi\|... - gi\|23125888\|ref\|ZP_00107803.1\| COG0438: Glycosyltransferase [Nostoc punctiforme PCC 73102], gi\|18668... gi\|16605561 - gi\|16605561\|emb\|CAC87818.1\| putative sucrose-phosphate synthase [Nostoc punctiforme PCC 73102]	247.0	[0..27]	[477..44]
gi\|46108156, gi\|... - gi\|46108156\|ref\|XP_381136.1\| hypothetical protein FG00960.1 [Gibberella zeae PH-1], gi\|42546668\|gb\|E...	247.0	[0..13]	[489..2]
gi\|125714043, gi... - gi\|67873277\|ref\|ZP_00503556.1\| Glycosyl transferase, group 1 [Clostridium thermocellum ATCC 27405], ...	247.0	[0..17]	[436..1]
GPI3_SCHPO - Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit OS=Schizosaccharomyces pombe (stra... gpi3 - pig-A	245.0	[0..25]	[496..7]
gi\|62359088, gi\|... - gi\|62359088\|gb\|AAX79535.1\| N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein, putative ... gi\|84043442 - gi\|84043442\|ref\|XP_951511.1\| N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein [Trypano...	244.0	[0..15]	[491..2]
SPT14 - UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosp...	244.0	[0..1]	[492..1]
gi\|39943844, gi\|... - gi\|39943844\|ref\|XP_361459.1\| hypothetical protein MGG_03933 [Magnaporthe grisea 70-15], gb\|EAA50174....	243.0	[0..14]	[487..2]
gi\|22330726 - gi\|22330726\|ref\|NP_178001.2\| glycosyl transferase family 1 protein [Arabidopsis thaliana]	242.0	[0..9]	[436..1]

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Predicted Domain #1

Region A:
Residues: [1-511]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQENSVHRS STKKTPIKIA FIHPDLGIGG AERLVVDAAV GLQSLGKEVV VFTSHCDKKH  60
   61 CFEEIRDGTI KVKVYGDWLP SSIFGRLSIF CSSLRQVYLT MILLTNYMHF DAIIVDQLST 120
  121 CVPFLLLASQ MILFYCHFPD KYLAKRGGIL KKLYRIPFDT VEAESVRLAD RIVVNSKFTA 180
  181 SVFKKAFPKI RKPLRIVHPC VDIEAASKPL EFQLPEKILY LRYSQRKLLI SVNRFERKKD 240
  241 IRLAIDAFSA LRDLSANRFP EYLLLVAGGY DIRVSENRRY LKELQEFCEQ KDLSYTTVKD 300
  301 NWDNITVAPS TNVLFLLSVP SKVRDALISS SRILLYTPEN EHFGIVPLEA MLRKVPVLAQ 360
  361 TNGGPLETVI DGKNGWLRPR DAKIWGNVIY EATTSTTYDT AAMGEAGSEW VKNEFSTDAM 420
  421 ARKFESEIMS GIRSITPEKR LMRRVNGLLA VFVLFMLFWG TCIIAATVPF AIIKLYFAQT 480
  481 YSSVKLGFML GTCIVSVSFL TFTVYAKLTN L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.522879
Match:	2bisA
Description:	Structure of glycogen synthase from Pyrococcus abyssi
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alpha-1,3-mannosyltransferase activity	6.58172475060696	bayes_pls_golite062009
glycolipid mannosyltransferase activity	5.39233021873725	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.70184884300914	bayes_pls_golite062009
mannosyltransferase activity	3.21859657603001	bayes_pls_golite062009
glycolipid 6-alpha-mannosyltransferase activity	2.81514353203234	bayes_pls_golite062009
glycolipid 3-alpha-mannosyltransferase activity	2.81514353203234	bayes_pls_golite062009
alpha-1,6-mannosyltransferase activity	2.81514353203234	bayes_pls_golite062009
catalytic activity	2.65148466065976	bayes_pls_golite062009
transferase activity	2.6268567881241	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.62403914335522	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.13085705769565	bayes_pls_golite062009
glycogen phosphorylase activity	1.55216954018473	bayes_pls_golite062009
glucosyltransferase activity	1.5162351691061	bayes_pls_golite062009
binding	1.22341386111754	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.21599854394093	bayes_pls_golite062009
phosphorylase activity	1.16838250569299	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.354187614795831	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.333194028937286	bayes_pls_golite062009
protein binding	0.0755094482594821	bayes_pls_golite062009
carbohydrate phosphatase activity	4.32270241054966E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: