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Protein Overview: SPAC824.02

General Information:
Name(s) found: SPAC824.02 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • GPI inositol deacylase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1142 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [ICLink to PubMed article]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    intrinsic to endoplasmic reticulum membrane [IEA]
    Biological Process: GPI anchor metabolic process [ISSLink to PubMed article]
    ER to Golgi vesicle-mediated transport [ISSLink to PubMed article]
    vesicle organization [ISSLink to PubMed article]
    phosphatidylinositol metabolic process [IC]
    intracellular protein transport [IEA]
    protein retention in ER lumen [ISSLink to PubMed article]
    Molecular Function: phosphatidylinositol deacylase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDDKGRSDT VNGYYISNSK LSSGFYKRNN ANTASNDEKP NLEQNDIPSV TSSGSSTPSS  60
   61 ISIEKEIKIS KGNVIVKAIR SWSLYVAIIA ILLLLVILHS FQGRPQDNGC GKSYVWPSYV 120
  121 RFVDFDERYT RFANKYSLYL YREKSVEESD EPSGIPILFI PGNAGSYKQV RAFAAQAAHV 180
  181 YANAYAEDAD GTLNAGKLVP DFFVVDFNED FSAFHGQTLL DQAEYVNDAI PYILSLYRQN 240
  241 RKISSEYDNE AFPPPTSVIL LGHSMGGIVA QATFTMKNYV DGSVNTLITL ATPHAMAPLP 300
  301 FDRHLVEFYE SIKNFWSQSF LLSPEENSLD DVLLVSIAGG GLDTHVVPEY SSISTFVPPS 360
  361 NGLMVFTSGI PSVWAEIDHQ AMAWCENFRR VLIRGIFAIM DARTSKCTVS LNLRKELLSR 420
  421 AYIQGSSFQN DITQISKPIA QYKALDLDLT YVYSEMPGQL LFLNQLGVSY IRHHIFPIPK 480
  481 PTSSIDRFEL LTDQPIDLSS SNIKVLACRL DPKIDNTISA LLENGNNKVI NANCHLLREL 540
  541 VTLLPASTAY TSSPYGGDSF YNYVLPKEKM DDYHFILVSD DSKAPASGFV VGGFSNVSLD 600
  601 PKTIKGSQIE LFKSGRKFQF DTKGSISKRF RFPGIQSSIM AYTISVTYEL YPGAVPQKEF 660
  661 TPMLKQSIES PFETKYHVNM SNTELSVHGI SPFMEFFGKE SEKSLTLEFF LNPAIYKSVY 720
  721 VSIQPSYYRS AGRLLMRYRT LLASFPVVVI SLAAYNQFRY FHYGSAYLSM SAALEVMIRK 780
  781 GLIKLLFLVS ILSIAFSYLI SRVELIVADG ADPVASWKIF AMMVPKSFWK QNHLLFGLQT 840
  841 AQFWFLAPLL TLMFVGLVIT ASVIILCVMH LLAFIYGIYL RYKGLTFTGV CQAVKFSFQC 900
  901 LRTRNTRKLD HGEFKKLSSF LSQRNMYYAN PSLCYVYGKK HMQARIIGIM LLLLMAMTVV 960
  961 PFQLVYGVAL CTQTVTTAKA LHLARFCTKS SHYRKKLWDF YNFSCTITIL MLLLAPLDFP1020
 1021 VLIVWARNLS MHWSIPFPTH HNFFSIIPFI LLTEILRTGK MLPRLNDVEY YINNVFLFLL1080
 1081 SFYSLIYGAE KPYLIHNVVG LYFFWLLFLY AKNGFFVQNI SKWPIIPRMK YFIKHKFLRS1140
 1141 IS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] MSA 1.090994 View MSA. No confident structure predictions are available.
    2 View Details [130..401] PSI-BLAST 30.09691 Lipase
    3 View Details [402..554] deduced N/A No confident structure predictions are available.
    4 View Details [555..687] deduced N/A No confident structure predictions are available.
    5 View Details [688..830] deduced N/A No confident structure predictions are available.
    6 View Details [831..959] MSA 1.02598 View MSA. No confident structure predictions are available.
    7 View Details [960..1142] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity
    		•  2.84700630261776 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.83678475999803 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.15349834890302 bayes_pls_golite062009
  • phospholipase activity
    		•  1.05835015160042 bayes_pls_golite062009
  • peptidase activity
    		•  0.863432317144146 bayes_pls_golite062009
  • lipase activity
    		•  0.849473630399459 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.424330502936163 bayes_pls_golite062009
  • binding
    		•  0.351031277062254 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.00117419779800387 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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