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Protein Overview: ell1

General Information:
Name(s) found: ell1 / SPBP23A10.14c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RNA polymerase II transcription elongation factor SpELL [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 533 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    ELL-EAF complex [IDALink to PubMed article]
    Biological Process: positive regulation of RNA elongation from RNA polymerase II promoter [ICLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article]
    RNA elongation from RNA polymerase II promoter [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: RNA polymerase II transcription elongation factor activity [IDALink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRNSSISDA LPVALGGNEE ESPLLMLVQL PKEFLEGYLS GTITDVSLEC SDVGTSILAN  60
   61 DRSYKCTSVP ETAPHEIYRL VDSNSLQLVG RVSQKLQLRR ELDSLTAERV KNRTQEAQKE 120
  121 KEEKRIVTLQ NDGGSKNTTA RKQKQLKKNG LRPLNTSASR IGLSSSPTNT PSPNLPVSQP 180
  181 SASPHYSGDK NSAKGIDLRT RVIQLLAIAP ETEDFLRLRT KASLSKLQAL LPEVAWKNNM 240
  241 NQWELLNPVY KDVRVFDWRP YSIADRNAVL SRMSNAFDNM QLPPDAPERS LLVSKQKNIT 300
  301 KLNNEKRIPP QLAQPTSHVP SFIDTNSPSM PSISSVSSYQ QQHRIPKLNA SNYSPLLSPS 360
  361 SHRKTSGNLS RTGSESSAVS LSDTTNLNTP ISDIPSPGSS TTCSNLSSPH IKRKSRSPPQ 420
  421 SLPSTPFPTS SSSTNGTLEP NANSPKKNEQ DAWIAKKRRQ QRYTTEEMRA LAKRFRETYP 480
  481 RYKNLYLKVS SYYDNNDTNN PNLNKLQDEL ISLHSQLKSW KNTLYDASSE LAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..172] deduced N/A No confident structure predictions are available.
    2 View Details [173..283] PSI-BLAST 21.30103 No description for 2doaA was found.
    3 View Details [284..533] MSA 5.177996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription elongation regulator activity
    		•  5.57922584114465 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription activator activity
    		•  3.70589483230587 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.58179858678904 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • RNA polymerase II transcription elongation factor activity
    		•  2.38180543580617 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.22485867684613 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.2723726467408 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
  • positive transcription elongation factor activity
    		•  0.13524243942225 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle