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Protein Overview: mak2

General Information:
Name(s) found: mak2 / SPAC27E2.09 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • histidine kinase Mak2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 2310 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    membrane [IEA]
    integral to membrane [IEA]
    Biological Process: stress-activated protein kinase signaling pathway [IGILink to PubMed article]
    two-component signal transduction system (phosphorelay) [TASLink to PubMed article]
    regulation of two-component signal transduction system (phosphorelay) [IC]
    cellular response to oxidative stress [IGILink to PubMed article]
    regulation of transcription, DNA-dependent [IEA]
    protein amino acid phosphorylation [TASLink to PubMed article]
    regulation of mitotic cell cycle [IGILink to PubMed article]
    regulation of conjugation with cellular fusion [IMPLink to PubMed article]
    Molecular Function: two-component sensor activity [NASLink to PubMed article]
    ATP binding [IEA]
    protein histidine kinase activity [TASLink to PubMed article]
    two-component response regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLYKSLDVA IDYAISQLGE FQFQPIRTQS NPSSLLSACL VRAVHVETRR KVIFKFSQQT  60
   61 FKLENEYFLL RQLSSHPNGR NYAIAPAYIL LLNETLGALI YDDPGPNILD EWLGNPNPLD 120
  121 LKLFLKFALG VSYVLCFLHE KKIVHGEIRL DTFHYDLNAP IHAKLLTIGS SVSPIRFTLS 180
  181 SLNWKRLYQV QNICHKLQFF SPEQIGNVGR PLDSRSDIYS LGILFYVILT KQYPWGGQSM 240
  241 RIVQSIHMRQ FPSVLPRRPD AFPALDQLIQ KMTAKSMNSR ISSATDLCYT IVELMQEFST 300
  301 ITSSPLLDQK LLSINKPQQE KLKFPKLLLT NSSDYVRIFH ELVAFSSKRD LLTSAKRVDK 360
  361 LPKQHLFKYR PVDNEATYCQ VVTVTGEKGS GKSNLLNAVA DEARKFGYFA MSSFKGHHFS 420
  421 PYSAIFKCVS LIMQQTLREE KQLVTDYFTS LWEFLGFQLI YMGELFEYVP ELNSLLSPKY 480
  481 NLHCKRENYF KLKKRDPQQF RSASGRLGFM VCLLEILSFT SRVRPVIIIL DELHLADHPS 540
  541 LSLIIGMISH RLPILLILAW DEPVMFKDFS KCLHEAPYAM VTDIRMNLFD RKNITEFLDS 600
  601 TLESPTQALG PLVLLMQKLS KGNPLVLKSL LLIAFANNGF AFHPKSSSWT YDLPVINRSF 660
  661 EALSSYDIPP LLASLLDALL PARCIEFLLW AALLVEPFPF ELLRLITTSM HLFIPKEEIL 720
  721 DFPLNVLQFD NDNESCQFSE TFFREGILSK ISLRRAESMH AQIAKELITG TAKEFYDIRT 780
  781 VHHILKGLGV IKKFDNTKPY ILALKESADA LMQFGSYEYA TELLKSCLFL LPRNFWNSKL 840
  841 YTRKDLISIH ISLAMCYWWS KDHENAIKVL KNPKLSSSNV YDYLPAFRLL TKIEYYKYQS 900
  901 LRSIDKAQEL LSNLGLKLKE PTDDVLREFY DRLSTKFLEC DFLVKQSEPL DRKRIDAISV 960
  961 ILSECGFVLF NFSQPYYYYF SFLLAEMYLR YGNPSLRYSV MFLASYCFVT RRKPEFLLRI1020
 1021 SQVDSDLFVI KDRSAVAHAE LIYWGLKREL CSTETGSAVT LESILLQCVM FGDKIYGAYC1080
 1081 LACLMAQRVF RGDHIHQLLL DQENSETLLL LWDCEPPFTY YLMLIRNSLL ALFGLTNNDD1140
 1141 PNNILTTKQR TQKDLHDKLT SKKVPCTFCC WYYAGIIFLN TLFHHYEYVM SIAQEVRKLV1200
 1201 DGKLYERYYL ITRSFIGVAA LQLLFYKKNI SEFEREKVED VAHWAQSSLS EMAKCFHAEL1260
 1261 YKLWVCLLEG LRQRNLGNYM EALRLFEKVT SMGASVFSPI EFPFVLELIG EFYYGRGHKF1320
 1321 LAKSYITRAL SCLKNIGCYG VENKLRSRYS DLISDVESRG TTVVSIATTT GDYAEKLKLL1380
 1381 RNQDINDFSL GLASYSDIFD KPLVTLPVKK SSAVDESEND FYDRNDEESF DIVSLVSVIK1440
 1441 CGQLLSSKLR LGPLLTTVIK LVIEYSQAKH AAIILKDASN YTLAAHGNVE KAESFEPPVI1500
 1501 LSQSDVKIPD SLLSEVFDHC RIVSLYTVSA SQDAELLRWL QEEHDMDFFA IIPLQFKESV1560
 1561 IGALYLCLSR RAIRTGNVTF LKLLSQQIAI SVSNALLFQS LRRTITDNVT LIELQRLSYQ1620
 1621 RYKAIEEKCI TLLDSLPCIV WTLDSDIGEI EYTNASKRNY FGVPEDCHDS LSWKTFIHPD1680
 1681 HHHQFQEKLL NLKTLELGDI ELLLRMEDGN YHWHLCRGLS FKEDANAKKW IVVCIDINDE1740
 1741 KEAREAAMHA VNLKTNFLAN MSHELRTPFS SFYGMLSLLS DTKLNEEQYD IVSTAKQSCT1800
 1801 SLVQIIDDLL NFSELKSGKM KLEPDKVFDV EENIADCIEL VYPSLSSKPV QISYDIYPNV1860
 1861 PALLAGDSAK LRQVITNLLG NSVKFTTEGH ILLRCMAIDE EINAEENQCK LRFEIEDTGI1920
 1921 GLKEEQLKLL FNPFTQVDGS TTRIYGGSGL GLSICLQICK IMDGDIGVQS VYGEGSTFWF1980
 1981 HVQLRNVTSK LSQKHFEESH ERFANIRQSL KNAKILVVKS FTTSRSIFRS LFSLAVVDTT2040
 2041 TIYSDIEQQL IDSLDKRQPY DFLCIEAASG QTEQIITQIL SNQKLNKVLL IVLLPSIQRT2100
 2101 KVRSDGDPFI TSLNKNQSRI FCFREPIRIS KLLQNFPALL SKWSTPTKLV EPSQFRASPR2160
 2161 KVDQAVVLSS EEKEILQKKY ALIAEDNLIA RKLLTKQLSN LGFQVHAAVD GVELVKMYEA2220
 2221 KQFGFYSVIF ADYHMPIRDG AEAVMDIRAY ERENNCSTPI PVIALTADIQ KSAKQRCLEV2280
 2281 GMNFYLTKPF TQKQLVNAVR EFVLLEKSAR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.64

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle