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Protein Overview: SPBC19C7.08c

General Information:
Name(s) found: SPBC19C7.08c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • leucine carboxyl methyltransferase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 681 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: C-terminal protein amino acid methylation [ICLink to PubMed article]
    wybutosine biosynthetic process [ISS]
    Molecular Function: C-terminal protein carboxyl methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKNQRKTK SKDREVRKTN DSSILSKASV EKCGYPGFTV GHSYYQPFIQ KSPRRSPSVN  60
   61 RGYWTRCMAI RFAVYQFLKN KTGKRKAIVN LGAGYDPLAF QLLSSHEYNT DDVVFYDVDY 120
  121 PETIENRVQM IRSDSFLSSI VLEDKEFDLD GTEIHTKNYH SFGCNLNLLN QLESCLEKYG 180
  181 IDYCNDAILF ISEVAAVYMP RQASEKLIRW MSKFPDAHSC FFEQIAPATF DHPFANVMVK 240
  241 HFKEWGTPLH GLYAYPTIES LKSRWVKNGW EYVEILDVCT FWNFLMDSKL KHLCEMVEPF 300
  301 DEWEEFYFFL QHYSIQHASS KLVGKYDLVE SPDPCMQYIR YVKSEIIFNN SPLTLRNSIY 360
  361 SLKRTDLPAC LKELPSLRLP AVCDLDDSVI VQGGLSTAGR SKDAYLISEK DDGSIMKITT 420
  421 DSLTSCMGQS VVSIDKKTCM FIGGRESPKK ILSSCIYFAD GNWSDFPSLP YASHRASSVS 480
  481 IKHNGSSYVV LLAGKPFGGC LIWSDSKRKW NTLKCKDPLF YSRWGACLHW SSKLKKGILC 540
  541 GGMNELNEPV REVLEWEMVL RDDDHFEIVT RVLNFDVQVE ILLSRIGSKV VFFGDDSKPI 600
  601 IVGGAAVFRT ILWEEESVCI NMNDYSVTGV CIEETEKRPV FTMFGISGMG NHLQIFGGGC 660
  661 ICFSFGSCLN ENATFYKLVS A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..326] PSI-BLAST 40.39794 No description for 2ob2A was found.
    2 View Details [327..681] PSI-BLAST 43.0 Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein methyltransferase activity
    		•  5.03267617653315 bayes_pls_golite062009
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  3.97658336148086 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  3.26663548517117 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  3.26663548517117 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.86617323549909 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  2.5931020126592 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  2.48017990451667 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  2.29640050660273 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.18991764495147 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  1.91133457052099 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  1.69391860928068 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  1.15089820497406 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • binding
    		•  0.777596419415505 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.533090627724779 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.469870476227704 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.469870476227704 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.469870476227704 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.455449410561251 bayes_pls_golite062009
  • RNA binding
    		•  0.417524996559564 bayes_pls_golite062009
  • tRNA (guanine) methyltransferase activity
    		•  0.203168546434167 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle