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Protein Overview: SPBC21B10.13c

General Information:
Name(s) found: SPBC21B10.13c [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • transcription factor, homeobox type [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IPILink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter, mitotic [IMPLink to PubMed article]
    negative regulation of gene-specific transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEA]
    protein binding [IPILink to PubMed article]
    specific RNA polymerase II transcription factor activity [IMPLink to PubMed article]
    sequence-specific DNA binding [ISSLink to PubMed article]
    specific transcriptional repressor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSDSPSKS GNTGKDLISN NEAKNHEDEE THQKKRRRRT TDAEATLLEQ YFLKTPKPSL  60
   61 IERQELSKKL KSSMTPRELQ IWFQNKRQSL RRSNCLSRNR LEGTGENSLL RRKSTLTLCE 120
  121 TSTGQAELFF QSWPLHSQSV VGEMIHHEQD DYNKENKQQK VVDTTKDISR GSNGNEDSAA 180
  181 HQELEECARS LVELQQQCND H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] PSI-BLAST 21.69897 Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
    2 View Details [104..201] MSA 4.074995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  1.04132983826241 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle